Veterinärmedizinische Universität Wien Forschungsinformationssystem VetDoc

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Hufnagl Karin,

** = Publikationen gelistet in SCI/SSCI/Pubmed

2021

Zeitschriftenaufsatz

** Afify, SM; Pali-Schöll, I; Hufnagl, K; Hofstetter, G; El-Bassuoni, MA; Roth-Walter, F; Jensen-Jarolim, E (2021): Bovine Holo-Beta-Lactoglobulin Cross-Protects Against Pollen Allergies in an Innate Manner in BALB/c Mice: Potential Model for the Farm Effect. Front Immunol. 2021; 12:611474
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** Roth-Walter, F; Afify, SM; Pacios, LF; Blokhuis, BR; Redegeld, F; Regner, A; Petje, LM; Fiocchi, A; Untersmayr, E; Dvorak, Z; Hufnagl, K; Pali-Schöll, I; Jensen-Jarolim, E (2021): Cow milk protein beta-lactoglobulin confers resilience against allergy by targeting complexed iron into immune cells. J Allergy Clin Immunol. 2021; 147(1):321-334.e4

Kongressbeitrag in einer Zeitschrift

** Hufnagl, K; Afify, SM; Ghosh, D; Wiederstein, M; Pali-Schöll, I; Hofstetter, G; Bianchini, R; Roth-Walter, F; Pacios, LF; Jensen-Jarolim, E (2021): The allergenic potential of lipocalin allergens can be diminished by retinoic acid. 33. Mainzer Allergie-Workshop – Frühjahrstagung der DGAKI, Mainz, Germany, MAR 25-26, 2021. Allergologie (44), 2 158-158.

** Jensen, SA; Pjevac, LM; Szikora, S; Sulzbacher, M; Bartosic, T; Pjevac, P; Hufnagl, K; Loy, A; Besser, G; Eckl-Dorner, J; Afify, SM; Krenn, CG; Roth, GA; Hann, S; Einwallner, E [and 2 others] (2021): Severity of allergic rhinitis is associated with ferroxidase ceruloplasmin and microbial communities not relying on iron. 33. Mainzer Allergie-Workshop – Frühjahrstagung der DGAKI, Mainz, Germany, MAR 25-26, 2021. Allergologie (44), 2 160-160.

** Köhler, VK; Crescioli, S; Fazekas-Singer, J; Bax, HJ; Hofer, G; Pranger, CL; Hufnagl, L; Bianchini, R; Flicker, S; Keller, W; Karagiannis, SN; Jensen-Jarolim, E (2021): Human IgE, IgG1, and IgG4 antibodies in the PIPEline for studying birch pollen allergy and tolerance. 33. Mainzer Allergie-Workshop – Frühjahrstagung der DGAKI, Mainz, Germany, MAR 25-26, 2021. Allergologie (44), 2 152-153.

2020

Zeitschriftenaufsatz

** Gotovina, J; Bianchini, R; Fazekas-Singer, J; Herrmann, I; Pellizzari, G; Haidl, ID; Hufnagl, K; Karagiannis, SN; Marshall, JS; Jensen-Jarolim, E (2020): Epinephrine drives human M2a allergic macrophages to a regulatory phenotype reducing mast cell degranulation in vitro. Allergy. 2020 75 (11) 2939-2942.
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** Hufnagl, K; Afify, SM; Braun, N; Wagner, S; Wallner, M; Hauser, M; Wiederstein, M; Gadermaier, G; Wildner, S; Redegeld, FA; Blokhuis, BR; Hofstetter, G; Pali-Schöll, I; Roth-Walter, F; Pacios, LF; Jensen-Jarolim, E (2020): Retinoic acid-loading of the major birch pollen allergen Bet v 1 may improve specific allergen immunotherapy: in silico, in vitro and in vivo data in BALB/c mice. Allergy. 2020 75 (8) 2073-2077.
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** Hufnagl, K; Pali-Schöll, I; Roth-Walter, F; Jensen-Jarolim, E (2020): Dysbiosis of the gut and lung microbiome has a role in asthma. Semin Immunopathol. 2020; 42(1):75-93
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** Köhler, VK; Crescioli, S; Fazekas-Singer, J; Bax, HJ; Hofer, G; Pranger, CL; Hufnagl, K; Bianchini, R; Flicker, S; Keller, W; Karagiannis, SN; Jensen-Jarolim, E (2020): Filling the Antibody Pipeline in Allergy: PIPE Cloning of IgE, IgG1 and IgG4 against the Major Birch Pollen Allergen Bet v 1. Int J Mol Sci. 2020; 21(16):E5693
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Kongressbeitrag in einer Zeitschrift

** Afify, SM; Pali-Scholl, I; Regner, A; Petje, LM; Hufnagl, K; Guethoff, S; Roth-Walter, F; Jensen-Jarolim, E (2020): Dietary supplementation with a new immune tablet reduces antigen presentation and allergic symptoms in a poly-sensitization BALB/c model. European-Academy-of-Allergology-and-Clinical-Immunology Digital Congress (EAACI), London, United Kingdom, JUN 06-08, 2020. Allergy (75), S109 312-313.

** Bartosik, T; Afify, SM; Petje, L; Bastl, M; Berger, U; Hufnagl, K; Einwallner, E; Muller, CA; Vyscocil, E; Guethoff, S; Jensen-Jarolim, E; Roth-Walter, F (2020): Dietary supplementation with a new immune tablet ameliorates human symptom load during birch pollen season: lower B-cell numbers yet with higher intracellular iron. European-Academy-of-Allergology-and-Clinical-Immunology Digital Congress (EAACI), London, United Kingdom, JUN 06-08, 2020. Allergy (75), S109 336-337.

** Hufnagl, K; Kromp, L; Bianchini, R; Wiederstein, M; Redegeld, F; Hofstetter, G; Roth-Walter, F; Pacios, L; Jensen-Jarolim, E (2020): The allergenic capacity of the major birch pollen allergen Bet v 1 can be impaired by vitamin D3 binding. European-Academy-of-Allergology-and-Clinical-Immunology Digital Congress (EAACI), London, United Kingdom, JUN 06-08, 2020. Allergy (75), S109 183-184.

** Korath, ADJ; Bastl, K; Hofstetter, G; Hufnagl, K; Bastl, M; Berger, UE; Jensen-Jarolim, E (2020): Qualitative and quantitative comparison of pollen allergen exposure between horses and human-A collaborative study with the Austrian pollen information service. European-Academy-of-Allergology-and-Clinical-Immunology Digital Congress (EAACI), London, United Kingdom, JUN 06-08, 2020. Allergy (75), S109 154-154.

** Pali-Scholl, I; Bianchini, R; Hofstetter, G; Winkler, S; Ahlers, S; Altemeier, T; Afify, SM; Hufnagl, K; Hann, S; Wittek, T; Kasper-Giebl, A; Pacios, LF; Roth-Walter, F; Vercelli, D; Von Mutius, E; Jensen-Jarolim, E (2020): Secretory beta-lactoglobulin associated with zinc in stable dust causes a Th1 immune bias in vitro and may contribute to the allergy protective effect of cattle farms. European-Academy-of-Allergology-and-Clinical-Immunology Digital Congress (EAACI), London, United Kingdom, JUN 06-08, 2020. Allergy (75), S109 145-145.

2019

Zeitschriftenaufsatz

** Bianchini, R; Roth-Walter, F; Ohradanova-Repic, A; Flicker, S; Hufnagl, K; Fischer, MB; Stockinger, H; Jensen-Jarolim, E (2019): IgG4 drives M2a macrophages to a regulatory M2b-like phenotype: potential implication in immune tolerance. Allergy. 2019; 74(3):483-494
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** Hufnagl, K; Jensen-Jarolim, E (2019): Does a carrot a day keep the allergy away? Immunol Lett. 2019; 206:54-58

Kongressbeitrag in einer Zeitschrift

** Afify, SM; Pali-Schöll, I; Hufnagl, K; Hofstetter, G; El Bassuoni, MA; Pacios, LF; Roth-Walter, F; Jensen-Jarolim, E (2019): Loading of beta-lactoglobulin confers cross-protection against sensitization to the major birch pollen allergen Bet V 1 in a BALB/c mouse model. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Lisbon, PORTUGAL, Portugal, JUN 01-05, 2019. Allergy (74), S106 91-91.

** Hufnagl, K; Afify, S; Braun, N; Wagner, S; Wiederstein, M; Hofstetter, G; Pali-Schöll, I; Roth-Walter, F; Pacios, LF; Jensen-Jarolim, E (2019): Retinoic acid determines the allergenicity of the major birch pollen allergen Bet v 1 in vitro and in vivo. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Lisbon, PORTUGAL, Portugal, JUN 01-05, 2019. Allergy (74), S106 335-336.

2018

Zeitschriftenaufsatz

** Herrmann, I; Gotovina, J; Fazekas-Singer, J; Fischer, MB; Hufnagl, K; Bianchini, R; Jensen-Jarolim, E (2018): Canine macrophages can like human macrophages be in vitro activated toward the M2a subtype relevant in allergy. Dev Comp Immunol. 2018; 82:118-127
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** Hufnagl, K; Ghosh, D; Wagner, S; Fiocchi, A; Dahdah, L; Bianchini, R; Braun, N; Steinborn, R; Hofer, M; Blaschitz, M; Roth, GA; Hofstetter, G; Roth-Walter, F; Pacios, LF; Jensen-Jarolim, E (2018): Retinoic acid prevents immunogenicity of milk lipocalin Bos d 5 through binding to its immunodominant T-cell epitope. Sci Rep. 2018; 8(1):1598
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** Hufnagl, K; Jensen-Jarolim, E (2018): Vitamin A and D in allergy: from experimental animal models and cellular studies to human disease. Allergo J Int. 2018; 27(3):72-78
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Kongressbeitrag in einer Zeitschrift

** Gotovina, J; Bianchini, R; Pranger, C; Fazekas-Singer, J; Herrmann, I; Pellizzari, G; Haidl, I; Hufnagl, K; Karagiannis, S; Marshall, J; Jensen-Jarolim, E (2018): Epinephrine-driven upregulation of beta 2-adrenergic receptor shifts human M2a allergic macrophages toward a regulatory phenotype. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Munich, GERMANY, Germany, MAY 26-30, 2018. Allergy (73), S105 797-797.

** Hufnagl, K; Braun, N; Wagner, S; Pacios, LF; Wiederstein, M; Wallner, M; Hofstetter, G; Roth-Walter, F; Jensen-Jarolim, E (2018): The major birch pollen allergen Bet v 1a displays reduced allergenic potential with retinoic acid in the pocket. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Munich, GERMANY, Germany, MAY 26-30, 2018. Allergy (73), S105 448-448.

2017

Zeitschriftenaufsatz

** Koper, I; Hufnagl, K; Ehmann, R (2017): Gender aspects and influence of hormones on bronchial asthma - Secondary publication and update. World Allergy Organ J. 2017; 10(1):46
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Kongressbeitrag in einer Zeitschrift

** Bianchini, R; Roth-Walter, F; Flicker, S; Ohradanova-Repic, A; Roth, G; Fischer, MB; Stockinger, H; Hufnagl, K; Jensen-Jarolim, E (2017): IgG4, but not IgG1, repolarizes pro-allergic M2a macrophages to a tolerogenic M2b-like phenotype: implications for allergen immunotherapy-mediated immune tolerance. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology, Helsinki, FINLAND, Finland, JUN 17-21, 2017. Allergy (72), S103 40-41.

** Hufnagl, K; Ghosh, D; Wagner, S; Fiocchi, A; Roth-Walter, F; Roth, G; Hofstetter, G; Pacios, L; Jensen-Jarolim, E (2017): Binding of the active vitamin A metabolite retinoic acid impairs immunogenicity of the major cows' milk allergen Bos D 5. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology, Helsinki, FINLAND, Finland, JUN 17-21, 2017. Allergy (72), S103 812-812.

Originalbeitrag in Sammelwerk

Hufnagl, K; Hirt, R; Robibaro, B (2017): Out of Breath: Asthma in Humans and Their Animals. IN: Jensen-Jarolim, E [Hrsg.]: Comparative medicine : disorders linking humans with their animals. Cham, Switzerland, Springer, pp. 71-85. ISBN: 978-3-319-47005-4.

2016

Kongressbeitrag in einer Zeitschrift

** Hufnagl, K; Wagner, S; Pacios, LF; Wallner, M; Wiederstein, M; Hofstetter, G; Roth-Walter, F; Jensen-Jarolim, E (2016): How to turn birch pollen allergen Bet v 1a as hypoallergenic as Bet v 1d By loading with retinoic acid. Meeting of the European-Academy-of-Allergy-and-Clinical-Immunology, Vienna, AUSTRIA, Austria, JUN 11-15, 2016. ALLERGY (71), S 505-506.

** Jensen-Jarolim, E; Roth-Walter, F; Pacios, LF; Wagner, S; Glenk, LM; Hofstetter, G; Palme, R; Roth, GA; Hufnagl, K; Bianchini, R (2016): IgG4 Drives M2 Macrophages to Cortisol, Lcn-2 and IL-10 Release: Implications in Maintenance of Tolerance and Allergen Immunotherapy. Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI), Los Angeles, CA, United States, MAR 04-07, 2016. J Allergy Clin Immun (137), 2 AB403-AB403.

** Wagner, S; Hufnagl, K; Pacios, LFF; Roth-Walter, F; Bianchini, R; Hofstetter, G; Jensen-Jarolim, E (2016): Binding of the Active Vitamin A Metabolite Retinoic Acid to the Major Cows Milk Allergen Bos d 5 Down-Regulates T-Cell Responses. Annual Meeting of the American-Academy-of-Allergy-Asthma-and-Immunology (AAAAI), Los Angeles, CA, United States, MAR 04-07, 2016. J Allergy Clin Immun (137), 2 AB407-AB407.

2015

** Hufnagl, K; Wagner, S; Roth-Walter, F; Hofstetter, G; Jensen-Jarolim, E (2015): Binding of retinoic acid to the major cow milk allergen Bos d 5 has an immunosuppressive effect on subsequent immune responses. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology, Barcelona, SPAIN, Spain, JUN 06-10, 2015. Allergy (70), S 158-158.

** Roth-Walter, F; Müller, H; Pacios, LF; Hofstetter, G; Bianchini, R; Hufnagl, K; Gotovina, J; Jensen-Jarolim, E (2015): Cortisol complexed with iron binds into the molecular pocket of the lipocalin-allergen Bos d 5. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology, Barcelona, SPAIN, Spain, JUN 06-10, 2015. Allergy (70), S 495-495.

2014

Zeitschriftenaufsatz

** Pichler, U; Hauser, M; Hofer, H; Himly, M; Hoflehner, E; Steiner, M; Mutschlechner, S; Hufnagl, K; Ebner, C; Mari, A; Briza, P; Bohle, B; Wiedermann, U; Ferreira, F; Wallner, M (2014): Allergen hybrids - next generation vaccines for Fagales pollen immunotherapy. Clin Exp Allergy. 2014; 44(3):438-449

2012

** Hoflehner, E; Hufnagl, K; Schabussova, I; Jasinska, J; Hoffmann-Sommergruber, K; Bohle, B; Maizels, RM; Wiedermann, U (2012): Prevention of birch pollen-related food allergy by mucosal treatment with multi-allergen-chimers in mice. Plos One. 2012; 7(6):E39409

** Schabussova, I; Hufnagl, K; Tang, ML; Hoflehner, E; Wagner, A; Loupal, G; Nutten, S; Zuercher, A; Mercenier, A; Wiedermann, U (2012): Perinatal maternal administration of Lactobacillus paracasei NCC 2461 prevents allergic inflammation in a mouse model of birch pollen allergy. PLoS One. 2012; 7(7):e40271
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2011

** Schabussova, I; Hufnagl, K; Wild, C; Nutten, S; Zuercher, AW; Mercenier, A; Wiedermann, U (2011): Distinctive anti-allergy properties of two probiotic bacterial strains in a mouse model of allergic poly-sensitization. Vaccine. 2011; 29(10):1981-1990

2008

** Hufnagl, K; Focke, M; Gruber, F; Hufnagl, P; Loupal, G; Scheiner, O; Wiedermann, U (2008): Airway inflammation induced after allergic poly-sensitization can be prevented by mucosal but not by systemic administration of poly-peptides. Clin Exp Allergy. 2008; 38(7):1192-1202

2007

** Bublin, M; Hoflehner, E; Wagner, B; Radauer, C; Wagner, S; Hufnagl, K; Allwardt, D; Kundi, M; Scheiner, O; Wiedermann, U; Breiteneder, H (2007): Use of a genetic cholera toxin B subunit/allergen fusion molecule as mucosal delivery system with immunosuppressive activity against Th2 immune responses. Vaccine. 2007; 25(50):8395-8404

** Wild, C; Wallner, M; Hufnagl, K; Fuchs, H; Hoffmann-Sommergruber, K; Breiteneder, H; Scheiner, O; Ferreira, F; Wiedermann, U (2007): A recombinant allergen chimer as novel mucosal vaccine candidate for prevention of multi-sensitivities. Allergy. 2007; 62(1):33-41

2006

** Winkler, B; Hufnagl, K; Spittler, A; Ploder, M; Kállay, E; Vrtala, S; Valenta, R; Kundi, M; Renz, H; Wiedermann, U (2006): The role of Foxp3+ T cells in long-term efficacy of prophylactic and therapeutic mucosal tolerance induction in mice. Allergy. 2006; 61(2):173-180

2005

** Bursch, W; Wastl, U; Hufnagl, K; Schulte-Hermann, R (2005): No increase of apoptosis in regressing mouse liver after withdrawal of growth stimuli or food restriction. Toxicol Sci. 2005; 85(1):507-514

** Hufnagl, K; Winkler, B; Focke, M; Valenta, R; Scheiner, O; Renz, H; Wiedermann, U (2005): Intranasal tolerance induction with polypeptides derived from 3 noncross-reactive major aeroallergens prevents allergic polysensitization in mice. J Allergy Clin Immunol. 2005; 116(2):370-376

2004

** Bursch, W; Grasl-Kraupp, B; Wastl, U; Hufnagl, K; Chabicovsky, M; Taper, H; Schulte-Hermann, R (2004): Role of apoptosis for mouse liver growth regulation and tumor promotion: comparative analysis of mice with high (C3H/He) and low (C57Bl/6J) cancer susceptibility. Toxicol Lett. 2004; 149(1-3):25-35

** Repa, A; Wild, C; Hufnagl, K; Winkler, B; Bohle, B; Pollak, A; Wiedermann, U (2004): Influence of the route of sensitization on local and systemic immune responses in a murine model of type I allergy. Clin Exp Immunol. 2004; 137(1):12-18

** Schausberger, E; Hufnagl, K; Parzefall, W; Gerner, C; Kandioler-Eckersberger, D; Wrba, F; Klimpfinger, M; Schulte-Hermann, R; Grasl-Kraupp, B (2004): Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor alpha. Br J Cancer. 2004; 91(11):1955-1963

** Wagner, B; Hufnagl, K; Radauer, C; Wagner, S; Baier, K; Scheiner, O; Wiedermann, U; Breiteneder, H (2004): Expression of the B subunit of the heat-labile enterotoxin of Escherichia coli in tobacco mosaic virus-infected Nicotiana benthamiana plants and its characterization as mucosal immunogen and adjuvant. J Immunol Methods. 2004; 287(1-2):203-215

2003

** Hufnagl, K; Wagner, B; Winkler, B; Baier, K; Hochreiter, R; Thalhamer, J; Kraft, D; Scheiner, O; Breiteneder, H; Wiedermann, U (2003): Induction of mucosal tolerance with recombinant Hev b 1 and recombinant Hev b 3 for prevention of latex allergy in BALB/c mice. Clin Exp Immunol. 2003; 133(2):170-176

2002

** Grasl-Kraupp, B; Schausberger, E; Hufnagl, K; Gerner, C; Löw-Baselli, A; Rossmanith, W; Parzefall, W; Schulte-Hermann, R (2002): A novel mechanism for mitogenic signaling via pro-transforming growth factor alpha within hepatocyte nuclei. Hepatology. 2002; 35(6):1372-1380

2001

** Hufnagl, K; Parzefall, W; Marian, B; Käfer, M; Bukowska, K; Schulte-Hermann, R; Grasl-Kraupp, B (2001): Role of transforming growth factor alpha and prostaglandins in preferential growth of preneoplastic rat hepatocytes. Carcinogenesis. 2001; 22(8):1247-1256

2000

** Löw-Baselli, A; Hufnagl, K; Parzefall, W; Schulte-Hermann, R; Grasl-Kraupp, B (2000): Initiated rat hepatocytes in primary culture: a novel tool to study alterations in growth control during the first stage of carcinogenesis. Carcinogenesis. 2000; 21(1):79-86

1998

** Schulte-Hermann, R; Hufnagl, K; Löw-Baselli, A; Rossmanith, W; Wagner, A; Ruttkay-Nedecky, B; Bursch, W; Müllauer, L; Parzefall, W; Grasl-Kraupp, B (1998): Apoptosis and hepatocarcinogenesis. Digestion. 1998; 59 Suppl 2:64-65

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