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Entwicklung von Mimotop-Vakzinen für präklinische und komparative Medizin Studien

Kurzbezeichnung
SFB F46 Mimotop-Vakzine
Koordination an der Vetmeduni Vienna
Jensen-Jarolim Erika
Laufzeit
01.01.16-31.07.20
Programm
FWF Spezialforschungsbereiche (SFB)
Art der Forschung
Grundlagenforschung
Beteiligte Vetmed-Organisationseinheiten
Messerli Forschungsinstitut, Abteilung für Komparative Medizin
Gefördert durch
FWF - Fonds zur Förderung der wissenschaftlichen Forschung, Sensengasse 1, 1090 Wien, Österreich

Link zur Projektdatenbank 'Project Finder'
43 Publikationen

Ondracek, AS; Heiden, D; Oostingh, GJ; Fuerst, E; Fazekas-Singer, J; Bergmayr, C; Rohrhofer, J; Jensen-Jarolim, E; Duschl, A; Untersmayr, E (2019): Immune Effects of the Nitrated Food Allergen Beta-Lactoglobulin in an Experimental Food Allergy Model. Nutrients. 2019; 11(10):2463
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Glenk, LM; Kothgassner, OD; Felnhofer, A; Gotovina, J; Pranger, CL; Jensen, AN; Mothes-Luksch, N; Goreis, A; Palme, R; Jensen-Jarolim, E (2019): Salivary Cortisol responses to acute stress vary between allergic and healthy individuals: The role of plasma oxytocin, emotion regulation strategies, reported stress and anxiety. Stress. 2019; 1-31
[Article in Press]

Pali-Schöll, I; Roth-Walter, F; Bianchini, R; Afify, SM; Hofstetter, G; Hann, S; Winkler, S; Ahlers, S; Wittek, T; Vercelli, D; Von Mutius, E; Jensen-Jarolim, E (2019): Beta-lactoglobulin (BLG) accumulates in stable dust associated with zinc: Potential implications for the allergy- and asthma-protective effect. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Lisbon, PORTUGAL, Portugal, JUN 01-05, 2019. Allergy (74), S106 848-848.

Pali-Schöll, I; Meinlschmidt, P; Larenas-Linnemann, D; Purschke, B; Hofstetter, G; Rodriguez-Monroy, FA; Einhorn, L; Mothes-Luksch, N; Jensen-Jarolim, E; Jäger, H (2019): Edible insects: Investigation of cross-reactivity and reduction of allergenicity. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Lisbon, PORTUGAL, Portugal, JUN 01-05, 2019. Allergy (74), S106 817-817.

Bianchini, R; Jordakieva, G; Groschopf, A; Piehslinger, J; Reichhold, D; Jensen, SAF; Klaus, A; Jensen-Jarolim, E (2019): Allergooncology-IgG4 negatively influences the ADCP and drives macrophages to a regulatory phenotype: Implications for tumour-mediated immune tolerance. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Lisbon, PORTUGAL, Portugal, JUN 01-05, 2019. Allergy (74), S106 137-138.

Afify, SM; Pali-Schöll, I; Hufnagl, K; Hofstetter, G; El Bassuoni, MA; Pacios, LF; Roth-Walter, F; Jensen-Jarolim, E (2019): Loading of beta-lactoglobulin confers cross-protection against sensitization to the major birch pollen allergen Bet V 1 in a BALB/c mouse model. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Lisbon, PORTUGAL, Portugal, JUN 01-05, 2019. Allergy (74), S106 91-91.

Jordakieva, G; Kundi, M; Untersmayr, E; Pali-Schöll, I; Reichardt, B; Jensen-Jarolim, E (2019): Country-wide medical records infer increased allergy risk of gastric acid inhibition. Nat Commun. 2019; 10(1):3298
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Ilieva, KM; Fazekas-Singer, J; Bax, HJ; Crescioli, S; Montero-Morales, L; Mele, S; Sow, HS; Stavraka, C; Josephs, DH; Spicer, JF; Steinkellner, H; Jensen-Jarolim, E; Tutt, ANJ; Karagiannis, SN (2019): AllergoOncology: Expression platform development and functional profiling of an anti-HER2 IgE antibody. Allergy. 2019; 74(10):1985-1989
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Pali-Schöll, I; Meinlschmidt, P; Larenas-Linnemann, D; Purschke, B; Hofstetter, G; Rodríguez-Monroy, FA; Einhorn, L; Mothes-Luksch, N; Jensen-Jarolim, E; Jäger, H (2019): Edible insects: Cross-recognition of IgE from crustacean- and house dust mite allergic patients, and reduction of allergenicity by food processing. World Allergy Organ J. 2019; 12(1):100006
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Pali-Schöll, I; Jensen-Jarolim, E (2019): Gender aspects in food allergy. Curr Opin Allergy Clin Immunol. 2019; 19(3):249-255

Pali-Schöll, I; Verhoeckx, K; Mafra, I; Bavaro, SL; Clare, Mills, EN; Monaci, L (2019): Allergenic and novel food proteins: State of the art and challenges in the allergenicity assessment. Trends in Food Science and Technology 2019; 84: 45-48

Pali-Schöll, I; Blank, S; Verhoeckx, K; Mueller, RS; Janda, J; Marti, E; Seida, AA; Rhyner, C; DeBoer, DJ; Jensen-Jarolim, E (2019): EAACI position paper: Comparing insect hypersensitivity induced by bite, sting, inhalation or ingestion in human beings and animals. Allergy. 2019; 74(5):874-887

Pfanzagl, B; Zevallos, VF; Schuppan, D; Pfragner, R; Jensen-Jarolim, E (2019): Histamine causes influx via T-type voltage-gated calcium channels in an enterochromaffin tumor cell line: potential therapeutic target in adverse food reactions. Am J Physiol Gastrointest Liver Physiol. 2019; 316(2):G291-G303

Bianchini, R; Roth-Walter, F; Ohradanova-Repic, A; Flicker, S; Hufnagl, K; Fischer, MB; Stockinger, H; Jensen-Jarolim, E (2019): IgG4 drives M2a macrophages to a regulatory M2b-like phenotype: potential implication in immune tolerance. Allergy. 2019; 74(3):483-494
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Hufnagl, K; Jensen-Jarolim, E (2019): Does a carrot a day keep the allergy away? Immunol Lett. 2019; 206:54-58

Roth-Walter, F; Schmutz, R; Mothes-Luksch, N; Lemell, P; Zieglmayer, P; Zieglmayer, R; Jensen-Jarolim, E (2018): Clinical efficacy of sublingual immunotherapy is associated with restoration of steady-state serum lipocalin 2 after SLIT: a pilot study. World Allergy Organ J. 2018; 11(1):21
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Mothes-Luksch, N; Jordakieva, G; Hinterhölzl, L; Jensen, AN; Hallmann, PK; Kundi, M; Jensen-Jarolim, E (2018): Allergy diagnosis from symptoms to molecules, or from molecules to symptoms: a comparative clinical study. World Allergy Organ J. 2018; 11(1):22
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Bianchini, R; Jordakieva, G; Groschopf, A; Piehslinger, J; Reichhold, D; Jensen, SAF; Klaus, A; Jensen-Jarolim, E (2018): AllergoOncology-IgG4 drives macrophages to a regulatory phenotype: Implications for tumour-mediated immune tolerance. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Munich, GERMANY, Germany, MAY 26-30, 2018. Allergy (73), S105 162-162.

Pali-Schöll, I; Meinlschmidt, P; Purschke, B; Hofstetter, G; Einhorn, L; Mothes-Luksch, N; Jensen-Jarolim, E; Jager, H (2018): Edible insects: Defining cross-reactivity and reducing allergenicity. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Munich, GERMANY, Germany, MAY 26-30, 2018. Allergy (73), S105 794-794.

Bianchini, R; Roth-Walter, F; Ohradanova-Repic, A; Flicker, S; Hufnagl, K; Fischer, MB; Stockinger, H; Jensen-Jarolim, E (2018): AllergoOncology-IgG4 drives macrophages to a regulatory phenotype: Implications for allergen immunotherapy-mediated immune tolerance. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Munich, GERMANY, Germany, MAY 26-30, 2018. Allergy (73), S105 160-160.

Afify, SM; Pali-Scholl, I; Hofstetter, G; Vidovic, A; Pacios, LF; Roth-Walter, F; Jensen-Jarolim, E (2018): The siderophore-iron loading state of the paradigmatic lipocalin BLG decides between subsequent protection or sensitization in a BALB/c mouse model. Congress of the European-Academy-of-Allergy-and-Clinical-Immunology (EAACI), Munich, GERMANY, Germany, MAY 26-30, 2018. Allergy (73), S105 851-852.

Pali-Schöll, I; Untersmayr, E; Klems, M; Jensen-Jarolim, E (2018): The Effect of Digestion and Digestibility on Allergenicity of Food. Nutrients. 2018; 10(9):
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Jordakieva, G; Jensen-Jarolim, E (2018): The impact of allergen exposure and specific immunotherapy on circulating blood cells in allergic rhinitis. World Allergy Organ J. 2018; 11(1):19
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Herrmann, Ina (2018): In-vitro Aktivierung und Charakterisierung von M2a Makrophagen in Hunden. Dissertation, Vet. Med. Univ. Wien, pp. 25.

Gotovina, J; Pranger, CL; Jensen, AN; Wagner, S; Kothgassner, OD; Mothes-Luksch, N; Palme, R; Larenas-Linnemann, D; Singh, J; Mösges, R; Felnhofer, A; Glenk, LM; Jensen-Jarolim, E (2018): Elevated oxytocin and noradrenaline indicate higher stress levels in allergic rhinitis patients: Implications for the skin prick diagnosis in a pilot study. PLoS One. 2018; 13(5):e0196879
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Fazekas-Singer, J; Singer, J; Ilieva, KM; Matz, M; Herrmann, I; Spillner, E; Karagiannis, SN; Jensen-Jarolim, E (2018): AllergoOncology: Generating a canine anticancer IgE against the epidermal growth factor receptor. J Allergy Clin Immunol. 2018; 142(3):973-976.e11
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Carvalho, MI; Bianchini, R; Fazekas-Singer, J; Herrmann, I; Flickinger, I; Thalhammer, JG; Pires, I; Jensen-Jarolim, E; Queiroga, FL (2018): Bidirectional Regulation of COX-2 Expression Between Cancer Cells and Macrophages. Anticancer Res. 2018; 38(5):2811-2817
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Hufnagl, K; Jensen-Jarolim, E (2018): Vitamin A and D in allergy: from experimental animal models and cellular studies to human disease. Allergo J Int. 2018; 27(3):72-78
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Pali-Schöll, I; Binder, R; Moens, Y; Polesny, F; Monsó, S (2019): Edible insects - defining knowledge gaps in biological and ethical considerations of entomophagy. Crit Rev Food Sci Nutr. 2019; 59(17):2760-2771
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Mueller, RS; Jensen-Jarolim, E; Roth-Walter, F; Marti, E; Janda, J; Seida, AA; DeBoer, D (2018): Allergen immunotherapy in people, dogs, cats and horses - differences, similarities and research needs. Allergy. 2018; 73(10):1989-1999

Diesner, SC; Bergmayr, C; Wang, XY; Heiden, D; Exenberger, S; Roth-Walter, F; Starkl, P; Ret, D; Pali-Schöll, I; Gabor, F; Untersmayr, E (2018): Characterization of Vibrio cholerae neuraminidase as an immunomodulator for novel formulation of oral allergy immunotherapy. Clin Immunol. 2018; 192:30-39
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Dölle, S; Welter, S; Ruppel, E; Lehmann, K; Schwarz, D; Jensen-Jarolim, E; Zieglmayer, P; Franken, P; Worm, M (2018): Clinical reactivity of celery cultivars in allergic patients: Role of Api g 1. Clin Exp Allergy. 2018; 48(4):424-432

Hufnagl, K; Ghosh, D; Wagner, S; Fiocchi, A; Dahdah, L; Bianchini, R; Braun, N; Steinborn, R; Hofer, M; Blaschitz, M; Roth, GA; Hofstetter, G; Roth-Walter, F; Pacios, LF; Jensen-Jarolim, E (2018): Retinoic acid prevents immunogenicity of milk lipocalin Bos d 5 through binding to its immunodominant T-cell epitope. Sci Rep. 2018; 8(1):1598
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Einhorn, L; Hofstetter, G; Brandt, S; Hainisch, EK; Fukuda, I; Kusano, K; Scheynius, A; Mittermann, I; Resch-Marat, Y; Vrtala, S; Valenta, R; Marti, E; Rhyner, C; Crameri, R; Satoh, R [and 6 others] (2018): Molecular allergen profiling in horses by microarray reveals Fag e 2 from buckwheat as a frequent sensitizer. Allergy. 2018; 73(7):1436-1446
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Herrmann, I; Gotovina, J; Fazekas-Singer, J; Fischer, MB; Hufnagl, K; Bianchini, R; Jensen-Jarolim, E (2018): Canine macrophages can like human macrophages be in vitro activated toward the M2a subtype relevant in allergy. Dev Comp Immunol. 2018; 82:118-127
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Raulf, M; Brüning, T; Jensen-Jarolim, E; van Kampen, V (2017): Gender-related aspects in occupational allergies - Secondary publication and update. World Allergy Organ J. 2017; 10(1):44
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Afify, SM; Pali-Schöll, I (2017): Adverse reactions to food: the female dominance - A secondary publication and update. World Allergy Organ J. 2017; 10(1):43
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Herrmann, I; Einhorn, L; Panakova, L (2017): Gender aspects in allergies of pets - A secondary publication and update. World Allergy Organ J. 2017; 10(1):42
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Roth-Walter, F; Pacios, LF; Bianchini, R; Jensen-Jarolim, E (2017): Linking iron-deficiency with allergy: role of molecular allergens and the microbiome. Metallomics. 2017; 9(12):1676-1692
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Jensen-Jarolim, E; Jensen, AN; Canonica, GW (2017): Debates in allergy medicine: Molecular allergy diagnosis with ISAC will replace screenings by skin prick test in the future. World Allergy Organ J. 2017; 10(1):33
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Jensen-Jarolim, E; Bax, HJ; Bianchini, R; Crescioli, S; Daniels-Wells, TR; Dombrowicz, D; Fiebiger, E; Gould, HJ; Irshad, S; Janda, J; Josephs, DH; Levi-Schaffer, F; O"Mahony, L; Pellizzari, G; Penichet, ML [and 6 others] (2018): AllergoOncology: Opposite outcomes of immune tolerance in allergy and cancer. Allergy. 2018; 73(2):328-340
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Pranger, Christina (2017): Effects of acute stress on the relieability of skin prick testing and mediator release: clinical study in healthy and allergic volunteers using the trier social stress test. Master Thesis, Vet. Med. Univ. Wien, pp. 59.

Oida, K; Einhorn, L; Herrmann, I; Panakova, L; Resch, Y; Vrtala, S; Hofstetter, G; Tanaka, A; Matsuda, H; Jensen-Jarolim, E (2017): Innate function of house dust mite allergens: robust enzymatic degradation of extracellular matrix at elevated pH. World Allergy Organ J. 2017; 10(1):23
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