University of Veterinary Medicine Vienna - Research portal

Diagrammed Link to Homepage University of Veterinary Medicine, Vienna

Salmonella Infantis in chickens: ability to survive - virulence - immune response

Salmonella spp. are considered to be one of the most common causes of food borne bacterial infections in humans. Salmonella enterica subspecies enterica includes more than 1400 non-typhoid serovars of which only a small amount counts for the majority of poultry asscociated isolates, namely S. Enteritidis, S. Typhimurium and S. Infantis. Although a reduction in infections with Salmonella can be observed over the last years the latest EFSA report (2016) announced an increase in human infections caused beside S. Enteritidis, S. Typhimurium mainly by S. Infantis. In Austria the same trend can be recognized ranking S. Infantis within the 4 most isolated serovars in humans. Poultry meat is regarded as the main reservoir for human infections. Over the last years, S. Infantis is found to be the most prevalent serovar in broilers in the EU. Eradication of S. Infantis from infected broiler flocks is hardly successful even by applying strict cleaning and desinfection procedures. A view publication indicated a higher tenacity of S. Infantis compared to other S. serovars.With the present study a focus will be on the in-vitro testing of bacterostatic and bacteriocidal activity of commercially available desinfectants which are actually used in the field. But also the influence of the host itself is not fully understood so far. The present project shall also contribute to gain more knowledge in regard to infection dynamics, organ affinity and immunology in infections with S. Infantis in broilers. Therefore, animal experiments are planned using different genetics of birds, different dosis of infections, different time points of infections and genetically diverse S. Infantis isolates. Additonally, by using sentinel birds and determination of S. Infantis load of air samples in these experiments the dynamics of infections shall be elucidated in a flock. The aim of the present project is to gain scientific data as basis for possible intervention strategies in regard to S. Infantis infections.
Project leader
Hess Claudia
Type of Research
Applied research
Vetmed Research Units
University Clinic for Poultry and Fish Medicine, Clinical Unit of Poultry Medicine
Projekt partner
Contact: Dr. Christian Kornschober
Österreichische Agentur für Gesundheit und Ernährungssicherheit GmbH, Robert-Koch-Gasse 17, A Mödling, Austria
Contact: Mag. Harald Schliessnig
Österreichische Qualitätsgeflügelvereinigung, Bahnhofstraße 9, 3430 Tulln, Austria
Funded by
Bundesministerium für Nachhaltigkeit und Tourismus, Stubenring 1, 1010 Wien, Austria
© University of Veterinary Medicine ViennaHelp and Downloads