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Incidence of AA amyloidosis in Austrian wildlife

Abstract
Systemic AA amyloidosis is the most common form of amyloidosis in human and veterinary medicine worldwide. Amyloidoses are s.c. protein-misfolding diseases, in which proteins are deposited intra- or extracellular in various organs leading to an impaired organ function, and even to organ failure. Chronic inflammations are the most common cause of this. However the incidence of idiopathic AA amyloidosis is increasing, and until today it is not clear why only few of those suffering from chronic inflammation develop this disease. Even though the mortality rate is decreasing due to better therapy it still is a fatal disease. In wildlife medicine the disease is known, however not much research has been performed in this area. One exception are cheetas (Acinonyx jubatus); here a connection between chronic gastritis and amyloidosis was proven. A possible transmission of the disease has been discussed for a long time. The possibility of an intra- and interspecies transmission has gained importance lately due to public health issues. Due to the discussed possibility of an infection over foodstuff and contact to animal sheddings, people in close contact to these animals (e.g. animal keepers, hunters, veterinarians), and people eating parts of animals that are not controlled are at a higher risk. Therefore this study aims to gather a first insight of the incidence of this entitiy in Austrian wildlife species.
Lemma
AA Amyloidose bei Wildtieren
Project leader
Posautz Annika
Duration
01.01.20-31.03.21
Programme
Hochschuljubil├Ąumsfonds der Stadt Wien
Type of Research
Basic research
Vetmed Research Units
Research Institute of Wildlife Ecology, Conservation Medicine
Funded by
Stadt Wien, Rathausstra├če 14-16, 1082 Wien, Austria
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