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Local antibody delivery to the gastrointestinal tract

Abstract
The aim of the project is to develop an oral administration system for therapeutic antibodies for the local treatment of gut diseases. Due to physico-chemical charachteristics, therapeutic antibodies may get inactivated through proteolytic enzymes in the gastrointestinal tract and therefor for the moment they have to be administered intravenously. An oral formulation would be cheaper for the health system and enhance the welfare of affected patients. This oral formulation could be used for the therapy of Morbus Crohn and Colitis ulcerosa.
Lemma
LAD-GI
Coordination for vetmeduni vienna
Schwarz Lukas
Coordination in general
Cyprumed GmbH, Kreidweg 27, 6461 Obsteig, Austria
Duration
01.07.20-30.06.21
Programme
FFG Basisprogramm Kleinprojekt
Type of Research
Applied research
Staff
Schwarz L.,
Vetmed Research Units
University Clinic for Swine
Funded by
FFG - Österreichische Forschungsförderungsgesellschaft, Sensengasse 1, 1090 Wien, Austria
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