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Endocrine control of canine hair growth

Abstract
Skin biopsies from 4 localisations (head, thorax, flank, perineum) of 3 male Beagle dogs were taken and the primary hair follicles isolated. Culture conditions were established to keep the hair follicles growing for up to 7 days. Hair follicles were incubated in supplemented medium with or without the addition of testosterone or oestradiol-17ß respectively in 3 different concentrations and the daily hair growth was monitored.
Testosterone and oestradiol-17ß inhibited in vitro the daily growth of hair follicles from the flank and the perineum, but this effect was not dose dependent. The daily growth of hair follicles from the head and the thorax was affected in a different manner (either stimulation or inhibition) by both steroids .
Project leader
Bamberg Elmar
Duration
01.01.00-31.12.01
Type of Research
Basic research
Staff
Bamberg E., Contact person
Vetmed Research Units
Institute for Medical Biochemistry
Projekt partner
Ludwig Boltzmann Institut für Veterinärmedizinische Endokrinologie, Veterinärplatz 1, A Wien, Austria
Funded by
OeNB Österreichische Nationalbank, Wien, Austria
3 Publications

Bratka-Robia, CB; Egerbacher, M; Helmreich, M; Mitteregger, G; Benesch, M; Bamberg, E (2002): Immunohistochemical localization of androgen and oestrogen receptors in canine hair follicles. Vet Dermatol. 2002; 13(2):113-118

Bratka-Robia, CB; Mitteregger, G; Aichinger, A; Egerbacher, M; Helmreich, M; Bamberg, E (2002): Primary cell culture and morphological characterization of canine dermal papilla cells and dermal fibroblasts. Vet Dermatol. 2002; 13(1):1-6

Egerbacher, M; Mitteregger, G; Bamberg, E (2001): Characterization of cultivated canine dermal papilla cells and dermal fibroblasts. 43 rd Int.Meeting of the European Tissue Culture Society, Cell Interactions and Cellular Complexity, Granada, 30.09.-03.10.2001. 43 rd Int.Meeting of the European Tissue Culture Society, Cell Interactions and Cellular Complexity, Granada, 30.09.-03.10.2001.

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