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Kynurenine Metabolism: Biochemical Studies in artificially infected pigs with Encephalomyocarditis

Abstract
This study should clarify the significances of kynurenine metabolism with respect to formation of behavioural and neuropathological signs within the central nervous system e.g. brain and spinal cord and peripheral system e.g. heart of experimentally or naturally EMCV infected piglets.
Lemma
Encephalomyocarditis-Virus / Schweine
Project leader
Baran Halina
Duration
02.01.02-02.01.04
Type of Research
Basic research
Vetmed Research Units
Institute of Pharmacology and Toxicology
Projekt partner
Funded by
FWF - Fonds zur Förderung der wissenschaftlichen Forschung, Sensengasse 1, 1090 Wien, Austria
8 Publications

Baran, H; Draxler, M; Kepplinger, B; Kahlbacher, H; Nowotny, N; Schmidt, P; Url, A; Schuh, M; Hofecker, G (2003): Kynurenine metabolism in piglet brain due to EMCV infection. Pharmacology. 2003; 69(4): 212-212.

Baran, H; Draxler, M; Kalbacher, H; Nowotny, N; Schmidt, P; Kepplinger, B; Url, A; Schuh, M; Hofecker, G (2003): Kynurenine aminotransferase I and II (KAT I and KAT II) in piglet's brain after Encephalomyocarditis (EMCV) infection. (33rd Annual Meeting, Society of Neuroscience, November New Orleans, LA, USA). Society for Neuroscience Abstract 33,(215).

Baran, H; Draxler, M; Kepplinger, B; Niedermüller, H (2004): Reduced glutamic acid decarboxylase (GAD) brain regions of piglets in experimental encephalomyocarditis (EMCV) model. 8th Congress of the European Federation of Neurological Societies, Paris, France, SEP 4-7, 2004. European Journal of Neurology (11), Suppl. 2 322-323.

Draxler, M; Kepplinger, B; Schmoll, F; Nowotny, N; Url, A; Schmidt, P; Strasser, A; Niedermüller, H; Schuh, M; Baran, H (2004): Choline acetyl transferase (ChAT) and glutamic acid decarboxylase (GAD) activities in control piglet brain. 18th IPVS Congress, Hamburg, 27.06. - 01.07.2004. 18th IPVS Congress, Hamburg, 27.06. - 01.07.2004.

Baran, H; Kepplinger, B; Lang, Ch; Draxler, M; Schmoll, F; Strasser, A; Schuh, M; Nowotny, N (2004): Enhancement of kynurenic acid (KYNA) and neopterin levels in serum of piglets after encephalomyocarditis virus (EMCV) infection. 18th IPVS Congress, Hamburg, 27.06. - 01.07.2004. 18th IPVS Congress, Hamburg, 27.06. - 01.07.2004.

Draxler, M; Baran, H; Schmoll, F; Nowotny, N; Kepplinger, B; Url, A; Schmidt, P; Strasser, A; Niedermüller, H; Hofecker, G; Schuh, M (2004): Affected choline acetyltransferase (ChAT) activity in piglet brain after encephalomyocarditis (EMCV) virus infection. 18th IPVS Congress, Hamburg, 27.06. - 01.07.2004. 18th IPVS Congress, Hamburg, 27.06. - 01.07.2004.

Baran, H; Draxler, M; Kepplinger, B (2004): Picornea encephalomyocarditis-evidences for neurochemical alterations. 12th Czech-Austrian Symposium on Medical Sciences and Art; 16.-17. April 2004; Metropol Ceske Budejovice/Budweis, Czech Republic. 2004.

Baran, H; Nowotny, N; Kepplinger, B; Scheider, H; Url, A; Schmidt, P; Kahlbacher, H; Nohl, H; Schuh, M (2001): Elevated kynurenate levels in serum of piglets infected with Encephalomyocarditis virus. 7th Symposium of the Austrian Pharmacological Society, Vienna, Austria, Austria, NOV 23–24, 2001. Pharmacology (63) 240-246.

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