University of Veterinary Medicine Vienna - Research portal

Diagrammed Link to Homepage University of Veterinary Medicine, Vienna

Neuroprotection in experimental ischemia

Cooperative studies on the prevention of ischemia induced injury by probing several putative neuro-protectants are conducted. Modelsystems in slices involve
- excitotoxic activation
- calcium-induced early postischemic signalling (PKC and calpains activation)
- modulation of glia-derived responses, such as anti-inflammatory treatments, blockade of death-domain-coupled receptors and protection offered by neurotrophins
- free radical-mediated injury (antioxidative treatments)
- mitochondrial permeability transition (by blocking megachannels by cyclosporine A)

Project leader
Rausch Wolf-Dieter
Type of Research
Basic research
Vetmed Research Units
Institute for Medical Biochemistry
Projekt partner
Polnische Akademie der Wissenschaften, Warschau, Poland
Funded by
Österreichischer Austauschdienst (OeAD) GmbH, Wien, Austria
© University of Veterinary Medicine ViennaHelp and DownloadsAccessibility statement