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Gewählte Publikation:

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Publikationstyp: Zeitschriftenaufsatz
Dokumentart: Originalarbeit

Publikationsjahr: 2012

AutorInnen: Filler, S; Alhaddad, H; Gandolfi, B; Kurushima, JD; Cortes, A; Veit, C; Lyons, LA; Brem, G

Titel: Selkirk Rex: morphological and genetic characterization of a new cat breed.

Quelle: J Hered. 2012; 103(5):727-733



Autor/innen der Vetmeduni Vienna:

Brem Gottfried

Beteiligte Vetmed-Organisationseinheiten
Institut für Tierzucht und Genetik


Abstract:
Rexoid, curly hair mutations have been selected to develop new domestic cat breeds. The Selkirk Rex is the most recently established curly-coated cat breed originating from a spontaneous mutation that was discovered in the United States in 1987. Unlike the earlier and well-established Cornish and Devon Rex breeds with curly-coat mutations, the Selkirk Rex mutation is suggested as autosomal dominant and has a different curl phenotype. This study provides a genetic analysis of the Selkirk Rex breed. An informal segregation analysis of genetically proven matings supported an autosomal, incomplete dominant expression of the curly trait in the Selkirk Rex. Homozygous curl cats can be distinguished from heterozygous cats by head and body type, as well as the presentation of the hair curl. Bayesian clustering of short tandem repeat (STR) genotypes from 31 cats that represent the future breeding stock supported the close relationship of the Selkirk Rex to the British Shorthair, Scottish Fold, Persian, and Exotic Shorthair, suggesting the Selkirk as part of the Persian breed family. The high heterozygosity of 0.630 and the low mean inbreeding coefficient of 0.057 suggest that Selkirk Rex has a diverse genetic foundation. A new locus for Selkirk autosomal dominant Rex, SADRE, is suggested for the curly trait.

Keywords Pubmed: Alleles
Animals
Bayes Theorem
Breeding*
Cats/classification*
Cats/genetics*
Female
Gene Frequency
Genotype
Hair/physiology*
Heterozygote
Male
Microsatellite Repeats
Mutation
Pedigree
Phenotype
Phylogeography
Polymorphism, Single Nucleotide
United States


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