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Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Originalarbeit

Jahr: 2021

AutorInnen: Blasi, B; Sipos, W; Knecht, C; Dürlinger, S; Ma, L; Cissé, OH; Nedorost, N; Matt, J; Weissenböck, H; Weissenbacher-Lang, C

Titel: Pneumocystis spp. in Pigs: A Longitudinal Quantitative Study and Co-Infection Assessment in Austrian Farms.

Quelle: J Fungi (Basel). 2021; 8(1):43

Autor/innen der Vetmeduni Vienna:

Blasi Barbara
Dürlinger Sophie
Knecht Christian
Matt Julia
Nedorost Nora
Sipos Wolfgang
Weissenbacher-Lang Christiane
Weissenböck Herbert

Beteiligte Vetmed-Organisationseinheiten
Institut für Pathologie
Universitätsklinik für Schweine

While Pneumocystis has been recognized as both a ubiquitous commensal fungus in immunocompetent mammalian hosts and a major opportunistic pathogen in humans responsible for severe pneumonias in immunocompromised patients, in pigs its epidemiology and association with pulmonary diseases have been rarely reported. Nevertheless, the fungus can be quite abundant in porcine populations with up to 51% of prevalence reported so far. The current study was undertaken to longitudinally quantify Pneumocystis carinii f. sp. suis and other pulmonary pathogens in a cohort of 50 pigs from five Austrian farms (i.e., 10 pigs per farm) with a history of respiratory disease at five time points between the first week and the fourth month of life. The fungus was present as early as the suckling period (16% and 26% of the animals in the first and the third week, respectively), yet not in a high amount. Over time, both the organism load (highest 4.4 × 105 copies/mL) and prevalence (up to 88% of positive animals in the third month) increased in each farm. The relative prevalence of various coinfection patterns was significantly different over time. The current study unravelled a complex co-infection history involving Pneumocystis and other pulmonary pathogens in pigs, suggesting a relevant role of the fungus in the respiratory disease scenario of this host.

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