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Publikationstyp: Zeitschriftenaufsatz
Dokumentart: Originalarbeit

Publikationsjahr: 2018

AutorInnen: Sommer, J; Fister, S; Gundolf, T; Bromberger, B; Mester, PJ; Witte, AK; Kalb, R; Rossmanith, P

Titel: Virucidal or Not Virucidal? That Is the Question-Predictability of Ionic Liquid"s Virucidal Potential in Biological Test Systems.

Quelle: Int J Mol Sci. 2018; 19(3):

Autor/innen der Vetmeduni Vienna:

Fister Susanne,
Gundolf Tobias,
Mester Patrick-Julian,
Rossmanith Peter,
Sommer Julia,
Witte Anna,

Beteiligte Vetmed-Organisationseinheiten
Institut für Milchhygiene,

For three decades now, ionic liquids (ILs), organic salts comprising only ions, have emerged as a new class of pharmaceuticals. Although recognition of the antimicrobial effects of ILs is growing rapidly, there is almost nothing known about their possible virucidal activities. This probably reflects the paucity of understanding virus inactivation. In this study, we performed a systematic analysis to determine the effect of specific structural motifs of ILs on three different biological test systems (viruses, bacteria and enzymes). Overall, the effects of 27 different ILs on two non-enveloped and one enveloped virus (P100, MS2 and Phi6), two Gram negative and one Gram positive bacteria (

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