Veterinärmedizinische Universität Wien Forschungsinformationssystem VetDoc

Grafischer Link zur Startseite der Vetmeduni Vienna

Gewählte Publikation:

Open Access Logo

Publikationstyp: Zeitschriftenaufsatz
Dokumentart: Originalarbeit

Publikationsjahr: 2018

AutorInnen: Harper, DJ; Augustin, M; Lichtenegger, A; Eugui, P; Reyes, C; Glösmann, M; Hitzenberger, CK; Baumann, B

Titel: White light polarization sensitive optical coherence tomography for sub-micron axial resolution and spectroscopic contrast in the murine retina.

Quelle: Biomed Opt Express. 2018; 9(5):2115-2129



Autor/innen der Vetmeduni Vienna:

Glösmann Martin,

Beteiligte Vetmed-Organisationseinheiten
VetCore,


Zugehörige(s) Projekt(e): Multifunktionelle OCT zur präklinischen Bildgebung im Maus- und Rattenauge


Abstract:
A white light polarization sensitive optical coherence tomography system has been developed, using a supercontinuum laser as the light source. By detecting backscattered light from 400 - 700 nm, an axial resolution of 1.0 µm in air was achieved. The system consists of a free-space interferometer and two homemade spectrometers that detect orthogonal polarization states. Following system specifications, images of a healthy murine retina as acquired by this non-contact system are presented, showing high resolution reflectivity images as well as spectroscopic and polarization sensitive contrast. Additional images of the very-low-density-lipoprotein-receptor (VLDLR) knockout mouse model were acquired. The high resolution allows the detection of small lesions in the retina.


© Veterinärmedizinische Universität Wien Hilfe und Downloads