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Gewählte Publikation:

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Publikationstyp: Zeitschriftenaufsatz
Dokumentart: Originalarbeit

Publikationsjahr: 2018

AutorInnen: Glueckert, R; Johnson Chacko, L; Schmidbauer, D; Potrusil, T; Pechriggl, EJ; Hoermann, R; Brenner, E; Reka, A; Schrott-Fischer, A; Handschuh, S

Titel: Visualization of the Membranous Labyrinth and Nerve Fiber Pathways in Human and Animal Inner Ears Using MicroCT Imaging.

Quelle: Front Neurosci. 2018; 12:501


Entstanden unter Nutzung der Ressourcen von
VetCore (VetImaging);

Autor/innen der Vetmeduni Vienna:

Handschuh Stephan,

Beteiligte Vetmed-Organisationseinheiten
VetCore,


Abstract:
Design and implantation of bionic implants for restoring impaired hair cell function relies on accurate knowledge about the microanatomy and nerve fiber pathways of the human inner ear and its variation. Non-destructive isotropic imaging of soft tissues of the inner ear with lab-based microscopic X-ray computed tomography (microCT) offers high resolution but requires contrast enhancement using compounds with high X-ray attenuation. We evaluated different contrast enhancement techniques in mice, cat, and human temporal bones to differentially visualize the membranous labyrinth, sensory epithelia, and their innervating nerves together with the facial nerve and middle ear. Lugol"s iodine potassium iodine (I


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