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Gewählte Publikation:

Publikationstyp: Zeitschriftenaufsatz
Dokumentart: Originalarbeit

Publikationsjahr: 2008

AutorInnen: Liebhart, D; Grabensteiner, E; Hess, M

Titel: A virulent mono-eukaryotic culture of Histomonas meleagridis is capable of inducing fatal histomonosis in different aged turkeys of both sexes, regardless of the infective dose.

Quelle: Avian Dis. 2008; 52(1):168-172



Autor/innen der Vetmeduni Vienna:

Grabensteiner Elvira
Hess Michael
Liebhart Dieter

Beteiligte Vetmed-Organisationseinheiten
Universitätsklinik für Geflügel und Fische


Abstract:
Histomonosis (syn. histomoniasis) is a parasitic disease which affects predominately turkeys but also other avian species. Concurrent with the ban of therapeutic and prophylactic substances, the disease, caused by the flagellated protozoon Histomonas meleagridis, is more frequently reported. Due to somewhat diverse results reported in the past, a well-characterized culture was used in the present study to investigate the possible influence of certain parameters on the outcome of the disease. For this study, turkeys were infected with different doses of the mono-eukaryotic culture Histomonas meleagridis/Turkey/Austria/2922-C6/04 using birds of both sexes at various ages. All study groups consisted of 14 birds, of which 10 birds were directly infected via the cloacal route and four birds were kept as in-contact birds. This scheme was used to investigate the pathogenicity of the cloned isolate in 1-day-old and 14-day-old turkeys. In 8-week-old turkeys, only eight birds out of 12 were infected. When 1-day-old and 8-week-old turkeys were infected with 10(4) histomonads per bird, all turkeys died between 11 and 21 days postinfection or had to be euthanatized due to their poor condition. In a group of 14 poults, infective doses of either 10 histomonads (100 histomonads among 10 birds) or 10(3) histomonads per bird had hardly any influence on the first notification of clinical signs. However, even though the onset of clinical signs and mortality was delayed with the lower dose, none of the birds survived the infection. As a consequence, no differences were noticed between male and female turkeys using the mono-eukaryotic culture of Histomonas meleagrigis/Turkey/Austria/2922-C6/04 in the current experimental setting.

Keywords Pubmed: Age Factors
Animals
Female
Male
Poultry Diseases/mortality
Poultry Diseases/parasitology*
Poultry Diseases/pathology
Protozoan Infections, Animal/mortality
Protozoan Infections, Animal/parasitology*
Protozoan Infections, Animal/pathology
Sex Factors
Trichomonadida/pathogenicity*
Turkeys/parasitology*
Virulence


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