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Gewählte Publikation:

Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Übersichtsarbeit

Jahr: 2009

AutorInnen: Marshall, W; Bockstahler, B; Hulse, D; Carmichael, S

Titel: A review of osteoarthritis and obesity: current understanding of the relationship and benefit of obesity treatment and prevention in the dog.

Quelle: Vet Comp Orthop Traumatol. 2009; 22(5):339-345



Autor/innen der Vetmeduni Vienna:

Bockstahler Barbara

Beteiligte Vetmed-Organisationseinheiten
Universitätsklinik für Kleintiere, Klinische Abteilung für Kleintierchirurgie
Universitätsklinik für Pferde, Klinische Abteilung für Pferdechirurgie


Abstract:
Obesity is an increasingly important health problem for both man and dog. Osteoarthritis (OA) is a significant cause of pain and disability in both species. A link between obesity and OA has been established in man, though the exact mechanism of the relationship remains to be fully elucidated - current research supports both biomechanical and biochemical theories. There is good evidence (class I*) to support weight loss as an effective treatment for human knee OA. In the dog, the relationship is just beginning to be investigated. The results of one study in dogs (class IV evidence*) suggest that preventing the development of overweightness and obesity reduces the prevalence of hip dysplasia and OA of the hip and other joints. Three other studies (class III and IV evidence*) support weight loss as an effective treatment for OA in affected overweight and obese dogs. Further research could yield greater understanding of the pathophysiology of this relationship, perhaps identifying novel therapeutic targets. Confirmation and better understanding of the positive effect of treating and preventing obesity on symptoms and prevalence of OA is likely to be valuable in the campaign against canine obesity.

Keywords Pubmed: Animals
Dog Diseases/pathology*
Dogs
Obesity/pathology
Obesity/veterinary*
Osteoarthritis/pathology
Osteoarthritis/veterinary*


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