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Gewählte Publikation:

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Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Originalarbeit

Jahr: 2009

AutorInnen: Palmieri, N; Schlötterer, C

Titel: Mapping accuracy of short reads from massively parallel sequencing and the implications for quantitative expression profiling.

Quelle: PLoS One. 2009; 4(7):e6323



Autor/innen der Vetmeduni Vienna:

Palmieri Nicola
Schlötterer Christian

Beteiligte Vetmed-Organisationseinheiten
Institut für Populationsgenetik


Abstract:
Massively parallel sequencing offers an enormous potential for expression profiling, in particular for interspecific comparisons. Currently, different platforms for massively parallel sequencing are available, which differ in read length and sequencing costs. The 454-technology offers the highest read length. The other sequencing technologies are more cost effective, on the expense of shorter reads. Reliable expression profiling by massively parallel sequencing depends crucially on the accuracy to which the reads could be mapped to the corresponding genes.

Keywords Pubmed: Animals
Arabidopsis/genetics
Drosophila melanogaster/genetics
Exons
Gene Expression Profiling*
Genome
Humans
Introns
Polymorphism, Genetic


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