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Gewählte Publikation:

Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Originalarbeit

Jahr: 2001

AutorInnen: Drillich, M; Beetz, O; Pfützner, A; Sabin, M; Sabin, HJ; Kutzer, P; Nattermann, H; Heuwieser, W

Titel: Evaluation of a systemic antibiotic treatment of toxic puerperal metritis in dairy cows.

Quelle: J Dairy Sci. 2001; 84(9):2010-2017

Autor/innen der Vetmeduni Vienna:

Drillich Marc

Diese Publikation wurde nicht im Namen der Vetmeduni Vienna erstellt und ist deshalb ausschließlich der persönlichen Publikationsliste des/der Autors/Autorin zugeordnet!

The objective of this study was to evaluate the efficacy and economic efficiency of a systemic treatment of toxic puerperal metritis in dairy cows with ceftiofur. Cows with abnormal vaginal discharge at a postpartum examination (d 4 to 6 after calving) and a rectal temperature > or = 39.5 degrees C were assigned to three treatment groups. Cows in group 1 (n = 70) received 600 mg of ceftiofur intramuscularly (i.m.) on 3 consecutive days. Cows in group 2 (n = 79) received an intrauterine treatment with antibiotic pills consisting of 2500 mg of ampicillin and 2500 mg of cloxacillin and an additional 6000 mg (i.m.) of ampicillin. This treatment was performed on 3 consecutive days. Cows in group 3 (n = 78) received the same intrauterine treatment as in group 2. In addition, 600 mg of ceftiofur was administered i.m. on 3 consecutive days. Body temperature was recorded daily for 6 d after first treatment. There were no significant differences among the groups regarding clinical efficacy at d 6 after first treatment. The cure rates based on rectal temperatures declining to below 39.5 degrees C on d 6 after treatment were 82.9, 84.8, and 84.6% for groups 1, 2, and 3, respectively. Reproductive performance did not differ significantly between group 1 and groups 2 and 3 for any of the measures tested. A financial analysis with 87 different cost scenarios demonstrated that a systemic treatment of toxic puerperal metritis in cattle with ceftiofur is an effective alternative to the combination of local and systemic treatments.

Keywords Pubmed: Ampicillin/economics
Ampicillin/therapeutic use
Anti-Bacterial Agents/economics
Anti-Bacterial Agents/therapeutic use*
Cattle Diseases/drug therapy*
Cattle Diseases/economics
Cephalosporins/therapeutic use*
Cloxacillin/therapeutic use
Costs and Cost Analysis
Drug Therapy, Combination
Endometritis/drug therapy
Injections, Intramuscular/veterinary
Puerperal Disorders/drug therapy
Puerperal Disorders/economics
Puerperal Disorders/veterinary*
Reproduction/drug effects*
Treatment Outcome

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