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Gewählte Publikation:

Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Originalarbeit

Jahr: 2012

AutorInnen: Hartmann, K; Stengel, C; Klein, D; Egberink, H; Balzarini, J

Titel: Efficacy and adverse effects of the antiviral compound plerixafor in feline immunodeficiency virus-infected cats.

Quelle: J Vet Intern Med. 2012; 26(3):483-490



Autor/innen der Vetmeduni Vienna:

Klein Dieter

Beteiligte Vetmed-Organisationseinheiten
VetCore


Abstract:
Bicyclam derivatives inhibit feline immunodeficiency virus (FIV) replication through selective blockage of chemokine receptor CXCR4.

Keywords Pubmed: Adenine/analogs & derivatives*
Adenine/therapeutic use
Animals
Anti-HIV Agents/therapeutic use*
Blood Cell Count/veterinary
Cats
Double-Blind Method
Drug Therapy, Combination/veterinary
Feline Acquired Immunodeficiency Syndrome/drug therapy*
Feline Acquired Immunodeficiency Syndrome/virology
Female
Heterocyclic Compounds/therapeutic use*
Immunodeficiency Virus, Feline/physiology*
Male
Organophosphonates/therapeutic use*
Prospective Studies
Receptors, CXCR4/antagonists & inhibitors
Statistics, Nonparametric
Viral Load/veterinary
Virus Replication/drug effects


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