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Gewählte Publikation:

Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Originalarbeit

Jahr: 2012

AutorInnen: Justa, N; Weber, K; Klein, D; Mueller, RS; Sauter-Louis, C; Hartmann, K

Titel: Efficacy and adverse effects of (R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine in feline immunodeficiency virus-infected cats.

Quelle: J Vet Intern Med. 2012; 26(6):1267-1273



Autor/innen der Vetmeduni Vienna:

Klein Dieter

Beteiligte Vetmed-Organisationseinheiten
VetCore


Abstract:
(R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine (PMPDAP) is active against feline immunodeficiency virus (FIV) in vitro, and is less toxic than other acyclic nucleoside phosphonates. Its efficacy in naturally infected cats has not been evaluated in large controlled studies.

Keywords Pubmed: Adenine/adverse effects
Adenine/analogs & derivatives*
Adenine/therapeutic use
Animals
Antiviral Agents/adverse effects
Antiviral Agents/therapeutic use*
Cat Diseases/drug therapy*
Cats
Double-Blind Method
Drug Administration Schedule
Female
Immunodeficiency Virus, Feline*
Lentivirus Infections/drug therapy
Lentivirus Infections/veterinary*
Lentivirus Infections/virology
Male
Organophosphorus Compounds/adverse effects
Organophosphorus Compounds/therapeutic use*
Viral Load


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