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Gewählte Publikation:

Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Originalarbeit

Jahr: 2012

AutorInnen: Starkl, P; Felix, F; Krishnamurthy, D; Stremnitzer, C; Roth-Walter, F; Prickett, SR; Voskamp, AL; Willensdorfer, A; Szalai, K; Weichselbaumer, M; O"Hehir, RE; Jensen-Jarolim, E

Titel: An unfolded variant of the major peanut allergen Ara h 2 with decreased anaphylactic potential.

Quelle: Clin Exp Allergy. 2012; 42(12):1801-1812



Autor/innen der Vetmeduni Vienna:

Jensen-Jarolim Erika
Roth-Walter Franziska
Szalai Krisztina
Weichselbaumer Marlene

Beteiligte Vetmed-Organisationseinheiten
Messerli Forschungsinstitut, Abteilung für Komparative Medizin


Abstract:
Peanut allergy causes severe type 1 hypersensitivity reactions and conventional immunotherapy against peanut allergy is associated with a high risk of anaphylaxis.

Keywords Pubmed: 2S Albumins, Plant/adverse effects
2S Albumins, Plant/chemistry*
2S Albumins, Plant/therapeutic use*
Adolescent
Alkylation
Anaphylaxis/prevention & control*
Animals
Antigens, Plant/adverse effects
Antigens, Plant/chemistry*
Antigens, Plant/therapeutic use*
Child
Child, Preschool
Circular Dichroism
Desensitization, Immunologic
Female
Glycoproteins/adverse effects
Glycoproteins/chemistry*
Glycoproteins/therapeutic use*
Humans
Male
Mice
Peanut Hypersensitivity/immunology
Peanut Hypersensitivity/prevention & control
Peanut Hypersensitivity/therapy*
Protein Unfolding
Spectrum Analysis/methods
Treatment Outcome


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