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Gewählte Publikation:

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Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Originalarbeit

Jahr: 2014

AutorInnen: Obistioiu, D; Cristina, RT; Schmerold, I; Chizzola, R; Stolze, K; Nichita, I; Chiurciu, V

Titel: Chemical characterization by GC-MS and in vitro activity against Candida albicans of volatile fractions prepared from Artemisia dracunculus, Artemisia abrotanum, Artemisia absinthium and Artemisia vulgaris.

Quelle: Chem Cent J. 2014; 8(1):6



Autor/innen der Vetmeduni Vienna:

Chizzola Remigius
Schmerold Ivo
Stolze Klaus

Beteiligte Vetmed-Organisationseinheiten
Institut für Pharmakologie und Toxikologie, Abteilung für Klinische Pharmakologie
Institut für Pharmakologie und Toxikologie
Institut für Tierernährung und funktionelle Pflanzenstoffe


Abstract:
A large number of essential oils is reported to have significant activity against Candida albicans. But the different chemical composition influences the degree of their activity. The intention of this study was to investigate the chemical composition and the activity against Candida albicans of volatile oils obtained from Artemisia dracunculus, A. abrotanum, A. absinthium and A. vulgaris (Asteraceae). The aim of the study was to identify new chemical compounds that have effect against C. albicans.The essential oils were obtained by hydrodistillation or extraction with dichloromethane (a new procedure we developed trying to obtain better, more separated compounds) from air dried above ground plant material and analyzed by GC-MS. Additionally commercial essential oils from the same species were tested. The Candida albicans inhibition studies were carried out by the paper disc diffusion method.


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