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Gewählte Publikation:

Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Originalarbeit

Jahr: 2015

AutorInnen: Gómez-Casado, C; Tordesillas, L; Kinkel, J; Starkl, P; Cuesta-Herranz, J; Roth-Walter F, ; Díaz-Perales, A; Jensen-Jarolim, E

Titel: Impact of glutathione on the allergenicity of the peach lipid transfer protein Pru p 3.

Quelle: J Investig Allergol Clin Immunol. 2015; 25(1):47-54


Autor/innen der Vetmeduni Vienna:

Jensen-Jarolim Erika
Roth-Walter Franziska

Beteiligte Vetmed-Organisationseinheiten
Messerli Forschungsinstitut, Abteilung für Komparative Medizin


Abstract:
The allergenic potential of proteins can be altered under various physicochemical conditions. Glutathione (GSH) is a reducing agent that is used as an antioxidant in food products. We aimed to characterize the natural folding of peach proteins and test the allergenicity of reduced and natural Pru p 3, the major peach allergen.

Keywords Pubmed: Adult
Allergens/chemistry
Allergens/immunology*
Allergens/metabolism
Antigens, Plant/chemistry
Antigens, Plant/immunology*
Antigens, Plant/metabolism
Carrier Proteins/chemistry
Carrier Proteins/immunology*
Carrier Proteins/metabolism
Cell Proliferation
Circular Dichroism
Cytokines/immunology
Female
Food Hypersensitivity/immunology
Glutathione/metabolism*
Humans
Leukocytes, Mononuclear/immunology
Male
Middle Aged
Plant Proteins/chemistry
Plant Proteins/immunology*
Plant Proteins/metabolism
Protein Conformation
Prunus/immunology*
Prunus/metabolism
Skin Tests


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