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Gewählte Publikation:

Publikationstyp: Zeitschriftenaufsatz
Dokumentart: Report

Publikationsjahr: 2016

AutorInnen: Wu, J; Stefaniak, J; Hafner, C; Schramel, JP; Kaun, C; Wojta, J; Ullrich, R; Tretter, VE; Markstaller, K; Klein, KU

Titel: Intermittent Hypoxia Causes Inflammation and Injury to Human Adult Cardiac Myocytes.

Quelle: Anesth Analg. 2016; 122(2):373-380



Autor/innen der Vetmeduni Vienna:

Schramel Johannes

Beteiligte Vetmed-Organisationseinheiten
Universitätsklinik für Kleintiere, Klinische Abteilung für Anästhesiologie und perioperative Intensivmedizin


Abstract:
Intermittent hypoxia may occur in a number of clinical scenarios, including interruption of myocardial blood flow or breathing disorders such as obstructive sleep apnea. Although intermittent hypoxia has been linked to cardiovascular and cerebrovascular disease, the effect of intermittent hypoxia on the human heart is not fully understood. Therefore, in the present study, we compared the cellular responses of cultured human adult cardiac myocytes (HACMs) exposed to intermittent hypoxia and different conditions of continuous hypoxia and normoxia.


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