Veterinärmedizinische Universität Wien Forschungsinformationssystem VetDoc

Grafischer Link zur Startseite der Vetmeduni Vienna

Gewählte Publikation:

Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Originalarbeit

Jahr: 2014

AutorInnen: Karamendin, K; Kydyrmanov, A; Kasymbekov, Y; Khan, E; Daulbayeva, K; Asanova, S; Zhumatov, K; Seidalina, A; Sayatov, M; Fereidouni, SR

Titel: Continuing evolution of equine influenza virus in Central Asia, 2007-2012.

Quelle: Arch Virol. 2014; 159(9):2321-2327



Autor/innen der Vetmeduni Vienna:

Fereidouni Sasan

Diese Publikation wurde nicht im Namen der Vetmeduni Vienna erstellt und ist deshalb ausschließlich der persönlichen Publikationsliste des/der Autors/Autorin zugeordnet!


Abstract:
Equine influenza (EI) continues to be an important respiratory pathogen of horses worldwide. Since 2007 several outbreaks of EI have occurred in Central Asian countries, including Kazakhstan, western Mongolia, India and western China. Phylogenetic analysis showed that two H3N8 equine influenza virus (EIV) isolates from Kazakhstan, A/equine/Almaty/26/2007 and A/equine/South Kazakhstan/236/12, were related to Florida sublineage 2, with high similarity to EIVs circulating in the same period in neighbouring countries. New outbreaks of EI during 2011 and 2012 in Kazakhstan and other Central Asian countries were caused by viruses of the same lineage. Genetic characterization of the viruses showed formation of a small EIV cluster with specific genetic signatures and continued evolution of this lineage in Central Asia between 2007 and 2012. The main genetic changes were observed in hemagglutinin gene without any antigenic drift. Although no vaccination policy was carried out in Kazakhstan, application of Florida clade 2-based vaccines is recommended.

Keywords Pubmed: Animals
Asia, Central/epidemiology
Cluster Analysis
Disease Outbreaks*
Evolution, Molecular*
Horse Diseases/epidemiology*
Horse Diseases/virology*
Horses
Influenza A Virus, H3N8 Subtype/classification
Influenza A Virus, H3N8 Subtype/genetics*
Influenza A Virus, H3N8 Subtype/isolation & purification
Molecular Sequence Data
Orthomyxoviridae Infections/epidemiology
Orthomyxoviridae Infections/veterinary*
Orthomyxoviridae Infections/virology
Phylogeny
RNA, Viral/genetics*
Sequence Analysis, DNA


© Veterinärmedizinische Universität Wien Hilfe und DownloadsErklärung zur Barrierefreiheit