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Gewählte Publikation:

Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Originalarbeit

Jahr: 2019

AutorInnen: Marasco, V; Boner, W; Griffiths, K; Heidinger, B; Monaghan, P

Titel: Intergenerational effects on offspring telomere length: interactions among maternal age, stress exposure and offspring sex.

Quelle: Proc Biol Sci. 2019; 286(1912):20191845



Autor/innen der Vetmeduni Vienna:

Marasco Valeria

Beteiligte Vetmed-Organisationseinheiten
Konrad Lorenz Institut für Vergleichende Verhaltensforschung, Abteilung für Ornithologie


Dryad Logo Daten sind in Dryad abgelegt. | DataLink: https://doi.org/10.5061/dryad.h8c9781


Zugehörige(s) Projekt(e): Ein Modell für das bessere Verständnis der Anpassung und der Veränderung beim Vogelzug


Abstract:
Offspring produced by older parents often have reduced longevity, termed the Lansing effect. Because adults usually have similar-aged mates, it is difficult to separate effects of maternal and paternal age, and environmental circumstances are also likely to influence offspring outcomes. The mechanisms underlying the Lansing effect are poorly understood. Variation in telomere length and loss, particularly in early life, is linked to longevity in many vertebrates, and therefore changes in offspring telomere dynamics could be very important in this context. We examined the effect of maternal age and environment on offspring telomere length in zebra finches. We kept mothers under either control (ad libitum food) or more challenging (unpredictable food) circumstances and experimentally minimized paternal age and mate choice effects. Irrespective of the maternal environment, there was a substantial negative effect of maternal age on offspring telomere length, evident in longitudinal and cross-sectional comparisons (average of 39% shorter). Furthermore, in young mothers, sons reared by challenged mothers had significantly shorter telomere lengths than sons reared by control mothers. This effect disappeared when the mothers were old, and was absent in daughters. These findings highlight the importance of telomere dynamics as inter-generational mediators of the evolutionary processes determining optimal age-specific reproductive effort and sex allocation.

Keywords Pubmed: Age Factors
Animals
Cross-Sectional Studies
Female
Finchesphysiology
Longitudinal Studies
Male
Maternal Age
Songbirdsphysiology
Stress, Physiological
Telomerephysiology

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