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Gewählte Publikation:

Publikationstyp: Zeitschriftenaufsatz
Dokumenttyp: Übersichtsarbeit

Jahr: 2007

AutorInnen: Nocentini, G; Cuzzocrea, S; Bianchini, R; Mazzon, E; Riccardi, C

Titel: Modulation of acute and chronic inflammation of the lung by GITR and its ligand.

Quelle: Ann N Y Acad Sci. 2007; 1107:380-91



Autor/innen der Vetmeduni Vienna:

Bianchini Rodolfo

Diese Publikation wurde nicht im Namen der Vetmeduni Vienna erstellt und ist deshalb ausschließlich der persönlichen Publikationsliste des/der Autors/Autorin zugeordnet!


Abstract:
Glucocorticoid-induced TNFR-related (GITR) protein, a member of the tumor necrosis factor receptor superfamily, is expressed in many components of the innate and adaptive immune system and modulates their activation following interaction with its ligand (GITRL). Here we review and discuss results described in previous publications where the role of the GITR/GITRL system in lung inflammation was evaluated using two experimental systems. We also discuss the proinflammatory role played by the GITR/GITRL system and the potential use of GITR fusion protein in inhibiting inflammation.

Keywords Pubmed: Acute Disease
Animals
Chronic Disease
Glucocorticoid-Induced TNFR-Related Proteinmetabolism
Humans
Ligands
Pneumoniaimmunologymetabolismpathology
Tumor Necrosis Factorsmetabolism

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