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Publication type: Journal Article
Document type: Full Paper

Year: 2011

Author(s): Malik, SB; Brochu, CD; Bilic, I; Yuan, J; Hess, M; Logsdon, JM; Carlton, JM

Title: Phylogeny of parasitic parabasalia and free-living relatives inferred from conventional markers vs. Rpb1, a single-copy gene.

Source: PLoS One. 2011; 6(6):e20774

Authors Vetmeduni Vienna:

Bilic Ivana
Hess Michael

Vetmed Research Units
University Clinic for Poultry and Fish Medicine, Clinical Unit of Poultry Medicine

Parabasalia are single-celled eukaryotes (protists) that are mainly comprised of endosymbionts of termites and wood roaches, intestinal commensals, human or veterinary parasites, and free-living species. Phylogenetic comparisons of parabasalids are typically based upon morphological characters and 18S ribosomal RNA gene sequence data (rDNA), while biochemical or molecular studies of parabasalids are limited to a few axenically cultivable parasites. These previous analyses and other studies based on PCR amplification of duplicated protein-coding genes are unable to fully resolve the evolutionary relationships of parabasalids. As a result, genetic studies of Parabasalia lag behind other organisms.

Keywords Pubmed: Animals
Gene Dosage/genetics*
Genes, Protozoan/genetics*
Genetic Markers
Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)/genetics
Molecular Sequence Data
Open Reading Frames/genetics
Protozoan Proteins/genetics
RNA Polymerase II/genetics*

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