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Publication type: Diploma Thesis

Year: 2011

Author(s): Strauch, Saskia

Title: Retrospektive Analyse der Resistenzlage verschiedener bakterieller Erreger der Lunge in Österreich in den Jahren 2007-2009 aus Proben zur Diagnostik von Atemwegserkrankungen beim Schwein.

Other title: Retrospective study that analyses the results of antibiotic sensitivity tests of respiratory tract pathogenes in pigs in the years 2007-2009

Source: Diplomarbeit, Vet. Med. Univ. Wien, pp. 39.


Ritzmann Mathias

Rosengarten Renate

Vetmed Research Units:
University Clinic for Swine

Graduation date: 26.11.11

Introduction: The importance of respiratory tract diseases in swine producing farms increased during the last years. The most important bacteria causing such infections are among others A. pyogenes, B. bronchiseptica, H. parasuis, P. multocida and S. suis as secundary pathogens, whereas A. pleuropneumoniae should be considered as a primary pathogenic agent. Not only to reduce the economic loss to the producer, but to optimize the animal welfare as well, it is important to treat these infections swiftly and successfully. The response to the treatment depends among others on the effectiveness of the applied antibiotics. To achieve satisfactory results, it is vital to monitor the incidence of resistant pathogens and to detect ineffective antibiotics as early as possible. In this retrospective study the results of antibiotic sensitivity tests of respiratory tract pathogens in pigs are analyzed from 2007 up to 2009. Material and methods: At the Clinic for Swine of the University of Veterinary Medicine in Vienna, 347 swine were examined in a diagnostic dissection. The following bacteriological investigations and resistance tests were carried out by the laboratory Labovet Gmbh in Vienna. The results were compared to each other in consideration of differences between the years, the age of the animals and the influence of pretreatment. Results and discussion: In the due course of the investigation period, bacterial agents were detected in as many as 186 animals. The incidence of the different pathogens was similar to the results of equivalent studies (PALZER, 2006; SCHERER, 2008; MAYRHOFER, 2009). The findings of the resistance tests present a remarkable high rate of resistant isolates to Tilmicosin in all bacteria. A. pleuropneumoniae isolates were less sensible for Tetracyclines as well, yet presented a good response to the other antimicrobials. Even though some authors reported a high sensitivity of A. pyogenes (YOSHIMURA et al., 2000; PEJSAK et al., 2006; MARKOWSKA-DANIEL et al., 2010), the results of this study indicated a high resistance rate to all tested antibiotics with the exception of Amoxicillin and Cefquinom. But neither Penicillines nor Cephalosporines worked out successfully against B. bronchiseptica isolates. High resistant rates were evaluated not only by this study, but by foreign analyses as well (SHIN et al., 2004; KADLEC et al., 2008; SCHWARZ et al., 2008; ZHAO et al., 2010). Only Doxycyclin showed a good performance against this agent in the analysed data in Austria. In this study, as well as in international publications, low rates of resistance were found for H. parasuis isolates (WISSING et al., 2001; AERESTRUP et al., 2004; MARTÌN DE LA FUENTE et al., 2007; MARKOWSKA-DANIEL et al., 2010; ZHOU et al., 2010). Even though there are foreign reports about a low resistance level of P. multocida isolates (WALLMANN et al., 2003; YANEDT et al., 2006; KASPAR, 2008; SELLYEI et al., 2009; MARKOWSKA-DANIEL et al., 2010), only Florfenicol, Sulfamethoxazol-Trimethoprim and Doxycyclin had worked out successfully during the course of this enquiry. S. suis isolates were sensible for Penicillines and Cephalosporines, but Tetracyclines, Makrolides and Lincospectin showed higher resistance rates. Foreign surveys gave approximately equivalent results for this causative agent (MARTEL et al., 2001; MARIE et al., 2002; VELA et al., 2005; WISSELINK et al., 2006; STEINACKER, 2008; ZHANG et al., 2008; MARKOWSKA-DANIEL et al., 2010).

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