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Publication type: Diploma Thesis

Year: 2012

Author(s): Ramsauer, Sophie

Title: Vorstudie zur intestinalen Hyperammonämie Messung des Ammoniakgehaltes bei Pferden mit Kolik.

Other title: Preliminary study of intestinal hyperammonaemia measurement of ammonia concentrations in horses with colic

Source: Diplomarbeit, Vet. Med. Univ. Wien, pp. 43.


Advisor(s):

Van Den Hoven Rene

Reviewer(s):
Iben Christine

Vetmed Research Units:
University Equine Clinic, Clinical Unit of Equine Internal Medicine


Graduation date: 23.11.12


Abstract:
Intestinal hyperammonaemia in horses can be caused by two different pathways: either increased production or increased absorption of ammonium. Intestinal hyperammonaemia is not a common diagnosis, only individual cases and small case series have been reported. Examined horses usually showed severe neurologic dysfunction, frequently in combination with signs of gastrointestinal dysfunction, but without evidence of hepatic disease. The objective of this study was to measure the blood ammonium concentration in a larger group of horses with colic and evaluate whether horses with colic or subgroups of these show elevated ammonia levels. Furthermore, it should be observed which causes of colic lead to hyperammonaemia and if ammonia could be used as a prognostic marker.


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