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Selected Publication:

Type of publication: Journal Article
Type of document: Full Paper

Year: 2010

Authors: Steinrigl, A; Ertl, R; Langbein, I; Klein, D

Title: Phylogenetic analysis suggests independent introduction of feline immunodeficiency virus clades A and B to Central Europe and identifies diverse variants of clade B.

Source: 9th International Feline Retrovirus Research Symposium, Vienna, AUSTRIA, Austria, AUG 24-27, 2008. Vet Immunol Immunopathol. 2010; 134(1-2):82-89

Authors Vetmeduni Vienna:

Ertl Reinhard
Klein Dieter
Steinrigl Adolf

Vetmed Research Units
Institute of Virology

Phylogenetic analysis of European feline immunodeficiency virus sequences confirms a highly distinct pattern in the occurrence of FIV-subtypes within Germany and Austria, indicating little mixing and at least two independent introductions of FIV. There is also evidence for a North to South gradient of FIV subtype distribution in Europe, with subtype A being more common in the North, while subtype B is prevalent in the South of Europe. In addition, among Austrian subtype B sequences, considerable differences from classical subtype B sequences were detected by bootscanning, which either suggests recombination with so far unrecognized subtypes, or a long period of independent evolution.

Keywords Pubmed: Animals
Cat Diseases/virology
DNA, Viral/genetics
Feline Acquired Immunodeficiency Syndrome/virology
Genetic Variation/genetics
Immunodeficiency Virus, Feline/genetics*
Molecular Sequence Data
Polymerase Chain Reaction/veterinary
Reassortant Viruses/genetics
Sequence Alignment

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