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Selected Publication:

Type of publication: Journal Article
Type of document: Full Paper

Year: 2015

Authors: Baumann, B; Schirmer, J; Rauscher, S; Fialová, S; Glösmann, M; Augustin, M; Pircher, M; Gröger, M; Hitzenberger, CK

Title: Melanin Pigmentation in Rat Eyes: In Vivo Imaging by Polarization-Sensitive Optical Coherence Tomography and Comparison to Histology.

Source: Invest Ophthalmol Vis Sci. 2015; 56(12):7462-7472



Authors Vetmeduni Vienna:

Glösmann Martin

Vetmed Research Units
VetCore


Abstract:
The purpose of this study was to demonstrate polarization-sensitive optical coherence tomography (PS-OCT) for imaging pigmented structures in the posterior eye segments of albino and pigmented rats and to correlate depolarization contrast of the retinal pigment epithelium (RPE) and choroid in in vivo PS-OCT to melanin pigmentation detected in postmortem histologic serial sections.

Keywords Pubmed: Albinism/pathology*
Animals
Disease Models, Animal
Fluorescein Angiography
Fundus Oculi
Male
Melanins/metabolism*
Rats
Rats, Inbred BN
Rats, Long-Evans
Rats, Sprague-Dawley
Retinal Pigment Epithelium/metabolism
Retinal Pigment Epithelium/pathology*
Tomography, Optical Coherence/methods*
Visual Acuity


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