University of Veterinary Medicine Vienna - Research portal

Selected Publication:

Open Access Logo

Publication type: Journal Article
Document type: Full Paper

Year: 2010

Author(s): Konaté, K; Souza, A; Coulibaly, AY; Meda, NT; Kiendrebeogo, M; Lamien-Meda, A; Millogo-Rasolodimby, J; Lamidi, M; Nacoulma, OG

Title: In vitro antioxidant, lipoxygenase and xanthine oxidase inhibitory activities of fractions from Cienfuegosia digitata Cav., Sida alba L. and Sida acuta Burn f. (Malvaceae).

Source: Pak J Biol Sci. 2010; 13(22):1092-1098



Authors Vetmeduni Vienna:

Lamien-Meda Aline

Vetmed Research Units
Institute of Animal Nutrition and Functional Plant Compounds


Abstract:
In this study polyphenol content, antioxidant activity, lipoxygenase (LOX) and Xanthine Oxidase (XO) inhibitory effects of n-hexane, dichloromethane, ethyl acetate and n-butanol fractions of aqueous acetone extracts from S. alba L., S. acuta Burn f and Cienfuegosia digitata Cav. were investigated. The total phenolics, flavonoids, flavonols and total tannins were determined by spectrophotometric methods using Folin-ciocalteu, AlCl3 reagents and tannic acid, respectively. The antioxidant potential was evaluated using three methods: inhibition of free radical 2,2-diphenyl-1-picrylhydramzyl (DPPH), ABTS radical cation decolorization assay and Iron (III) to iron (II) reduction activity (FRAP). For enzymatic activity, lipoxygenase and xanthine oxidase inhibitory activities were used. This study shows a relationship between polyphenol contents, antioxidant and enzymatic activities. Present results showed that ethyl acetate and dichloromethane fractions elicit the highest polyphenol content, antioxidant and enzymatic activities.

Keywords Pubmed: Antioxidants/pharmacology*
Lipoxygenases/drug effects*
Malvaceae/chemistry*
Xanthine Oxidase/antagonists & inhibitors*


© University of Veterinary Medicine ViennaHelp and Downloads