The positive properties of genus Plantago are used in many different ways. It is used as a
phytotherapeutic to treat respiratory diseases in human and animals, it is used in animal
feeding and it is part of dietary supplements. For this thesis the phenolic compounds of
twelve different Plantago species were analyzed by HPLC and the total content of phenolics
and the antioxidant activity were measured by spectrophotometric methods. Differences
and similarities of both, the various species and their different parts (leaves, stem with
flowers/fruits, roots) were shown. The HPLC analyses showed that a wide range of phenolic
compounds was present. The phenylethanoid glycoside verbascoside was identified as a
marker for genus Plantago, because it was found in all samples, but it couldnt be used to
differentiate between the different species. In most samples verbascoside was the main
phenolic compound, but there were some cases where other compounds (peak H and J) with
similar UV-spectrum dominated.
It was shown, that the content of different phenolic substances, the total content of
phenolics and the antioxidant activity varies between and within the individual Plantago
species and between the analyzed parts of the plants. This makes it impossible to give a
definite statement about the correlation between phenolic compounds and effects.
Therefore tests with a larger amount of plant material and more information would be
needed. However, the roots should get more attention by using Plantago because partially
they showed a higher antioxidant potency than aerial parts of the plant.