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Publication type: Journal Article
Document type: Review

Year: 2019

Author(s): Ashfaq, H; Soliman, H; Saleh, M; El-Matbouli, M

Title: CD4: a vital player in the teleost fish immune system.

Source: Vet Res. 2019; 50(1):1



Authors Vetmeduni Vienna:

Ashfaq Hassan
El-Matbouli Mansour
Saleh Mona
Soliman Hatem

Vetmed Research Units
Clinical Unit of Fish Medicine


Project(s): The role of SOCS Proteins in salmonid whirling disease


Abstract:
CD4 is a nonpolymorphic transmembrane glycoprotein molecule that is expressed on the surface of T-helper cells and plays an essential role in the immune response. It functions as a coreceptor with the T-cell receptor by binding to major histocompatibility complex class II on the surface of dendritic cells that present antigens. CD4


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