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Publication type: Doctoral Thesis

Year: 2006

Author(s): Schoder, D

Title: Untersuchungen zum Antikörper-Status gegen Hundestaupevirus und Canines Parvovirus 2 bei Hunden in Niederösterreich und Wien nach unterschiedlichen Impfintervallen.

Source: Dissertation, Vet. Med. Univ. Wien, pp. 100.

Advisor(s):

Möstl Karin


Abstract:
The aim of this study was to get more information about the antibody status against Canine Distemper Virus (CDV) and Canine Parvovirus-2 (CPV-2) in Austrian dogs with a regular basic immunisation and a varying number of and interval since booster vaccinations. Therefore antibody titres to CDV and CPV-2 were determined in 147 vaccinated dogs. All animals were ambulatory patients of veterinary clinics in Vienna and Lower Austria presented for routine health check or revaccination. All dogs had completed their basic vaccination consisting of at least 2 vaccinations in their first year of life and the first booster vaccination after one year. The time interval between antibody measurement and last vaccination varied from 1 to 98 months. Vaccination histories were available of every dog. Antibody titres of >= 1:80 for CDV (immunofluorescent test) and > 1:80 for CPV-2 (haemagglutination inhibition test) were considered as indicative of protection. Protective antibody titres against CDV were found in 89.1 % of the animals and in 99.3 % against CPV-2. The geometric mean titres (GMT) decreased with increasing time interval between testing and the last vaccination against both viruses. Whereas for CPV-2 all dogs with only one exception were still in the protective range, CDV antibody titres of dogs with a vaccination interval longer than 18 months were < 1:80 in 29 % of the cases. Statistical evaluation of risk showed that dogs not vaccinated against CDV for longer than 24 months, had a nearly 5 times higher risk for a non-protective CDV antibody titre compared with those dogs, which had received their last CDV vaccination within a 2 year interval. Concerning CPV-2 it could be shown that our dog population exhibits antibody titres indicative of protection by means of regularly performed vaccinations and therefore the revaccination interval for CPV-2 can be prolonged. But it becomes further obvious that booster vaccinations against CDV have to be considered quite different. The results underline the importance of an individual approach to preventive health care and annual vaccinations. Serologic testing may offer an orientation about the immune status of the individual animal.

Keywords:
antibody titre / canine distemper virus / canine parvovirus-2 / vaccination / dog


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