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Selected Publication:

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Type of publication: Diploma Thesis
Type of document:

Year: 2009

Authors: Haymerle, Agnes

Title: Human exposures to immobilising agents: results of an online survey.

Source: Diplomarbeit, Vet. Med. Univ. Wien, pp. 28.


Authors Vetmeduni Vienna:

Haymerle Agnes

Advisor(s):
Walzer Christian

Reviewer(s):
Moens Yves

Vetmed Research Units:
Research Institute of Wildlife Ecology


Abstract:
Potent injectable anaesthetics are essential for working with wildlife yet they bear an inherent risk of human incidents and injuries. Accidental and intentional exposures are evident in literature. By critical analysis we consolidated published cases found in the literature and results from an online questionnaire to provide a more objective approach to the issue of human exposure. The Modified Glasgow Coma Scale (GCS) was used to rank the cases according to their severity. Intoxications with potent opioids like etorphine, carfentanil and thiafentanil need to be antagonised with naloxone, nalmefene or naltrexone, and not with antagonists with agonistic properties, such as diprenorphine. Concerning the α2-agonists xylazine, detomidine, medetomidine, and romifidine, there is no antagonist accredited for human use. Atipamezole, the specific α2-antagonist, is widely used in veterinary medicine and has been used experimentally to reverse dexmetomidine in a human study. The high concentrations of α2-agonists being used in zoo and wildlife medicine calls for accreditation of atipamezole in cases of human exposure. Preventive measures, like wearing gloves and eye protection, to reduce the risk of exposure, need to be used more regularly. Knowledge and availability of the appropriate antagonist are essential in case of human intoxication with injectable anaesthetics.


Publication(s) resulting from University thesis:

Haymerle, A; Fahlman, A; Walzer, C (2010): Human exposures to immobilising agents: results of an online survey. Vet Rec. 2010; 167(9):327-332

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