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Publication type: Doctoral Thesis

Year: 2011

Author(s): Spiss, Sabine

Title: Coronavirus-Infektionen österreichischer Hunde: Serologische und virologische Untersuchungen der Prävalenz und klinischen Bedeutung von Alpha- und Betacoronaviren bei respiratorischen und enteralen Erkrankungen.

Other title: Enteric and respiratory coronavirus infections in Austrian dogs: serological and virological investigations of prevalence and clinical importance in respiratory and enteric disease

Source: Dissertation, Vet. Med. Univ. Wien, pp. 90.


Advisor(s):

Möstl Karin

Reviewer(s):
Schmidt Peter

Vetmed Research Units:
Institute of Virology


Graduation date: 17.11.11


Abstract:
In order to obtain first epidemiological data of the prevalence of betacoronavirus infection in Austrian dog populations sera and conjunctival and oropharyngeal swabs of dogs were investigated for canine respiratory coronavirus (CRCoV). Furthermore 10 years following the last serological investigations, the seroprevalence of canine enteric coronavirus (CECoV) was reassessed. Finally the role of coronaviruses and canine parvovirus type 2 (CPV-2) in gastroenteritis was evaluated in 2 groups of dogs, one without and one with enteric signs. For CRCoV, a seroprevalence of 61.2 % and a virus prevalence of 8.8 % in dogs with respiratory symptoms could be detected. For CECoV, a seroprevalence of 88.2 %, a virus prevalence of 31.3 % in dogs with diarrheal disease and of 0 % in dogs without gastroenteric signs could be found, whereas 40.6 % in the control group and 87.5 % in the patient group were found to be positive for CPV-2 specific nucleic acid. Additional epidemiological studies are required to determine the biological and immunological roles of single and combined CRCoV infections.

Keywords:
dog, coronavirus, canine infectious respiratory disease (CIRD), diarrhea, Austria


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