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Selected Publication:

Publication type: Diploma Thesis

Year: 2013

Author(s): Firth, Clair

Title: Prevalence of feline leukaemia virus (antigenaemic animals) among owned cats in Vienna: a retrospective analysis of serum samples routinely tested for the presence of FeLV antigen between 1996 and 2011.

Source: Diplomarbeit, Vet. Med. Univ. Wien, pp. 63.


Authors Vetmeduni Vienna:

Firth Clair

Advisor(s):
Möstl Karin

Reviewer(s):
Rümenapf Hans Tillmann

Vetmed Research Units:
Institute of Virology


Graduation date: 24.10.14


Abstract:
This was a retrospective study including samples from all owned cats serologically tested for feline leukemia virus antigen by the Department for Clinical Virology at the University of Veterinary Medicine, Vienna, Austria, between 1996 and 2011. The aim of this retrospective analysis was to determine the seroprevalence of feline leukaemia virus infection (antigenaemic animals) among owned cats in Vienna and the surrounding area. As the annual number of samples tested had reduced substantially over the 16 year period, it was decided to pool a number of years together (2008-2011) to statistically compare data with the baseline year of 1996. The null hypothesis stated that there was no statistically significant difference between the prevalence of FeLV-antigenaemic cats tested in Vienna in 1996 and in 2008-2011. Between 1996 and 2011, 4465 samples were analysed. The overall prevalence over the entire 16 year period was 5.58% (95% CI: 5.57%; 5.59%); the annual feline leukaemia virus prevalence in Austria between 1996 and 2011 was found to be highly variable, with a minimum of 2.76% in 1998 and a maximum of 7.67% in 1997. The prevalence of FeLV-antigenaemic animals in 1996 was 7.4% compared to 5.9% over the period 2008-2011. The Chi-squared value (with Yates correction) equals 1.135 with 1 degree of freedom. The difference between 1996 and 2008-2011 is 1.5% (95% CI: -1.3%; 4.3%) and is not statistically significant at the 5% level (p-value = 0.3036). Similarly, no statistically significant difference could be determined between FeLV-antigenaemic cats in 1996 and 2008-2011 with respect to either age or sex. To conclude, this retrospective analysis determined that there was no statistically significant difference between the prevalence of FeLV-antigenaemic cats tested in Vienna in 1996 and in 2008-2011 and the null hypothesis could therefore not be rejected.


Publication(s) resulting from University thesis:

Firth, CL; Möstl, K (2015): A survey of feline leukaemia virus antigenaemia among cats in eastern Austria: a retrospective analysis of serum samples routinely tested between 1996 and 2011. JFMS Open Rep. 2017; 1(2):2055116915598336
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