Vergleich pflanzlicher Nahrungsergänzungsmittel bzw. Futtermittel mit Human- bzw. Veterinär-Phytopharmaka von den Pflanzen Ginkgo, Preiselbeere und Weinrebe mit besonderem Augenmerk auf Ginkgolsäuren.
Comparison of nutraceuticals, feed stuff, human and veterinary phytopharmaceuticals containing the plants ginkgo, cranberries/lingonberries and grape wine with special regards to ginkgolic acids.
Diplomarbeit, Vet. Med. Univ. Wien, pp. 168.
The aim of this work was to compare nutritional supplements for humans
and animals with pharmaceutical products. The plants in question were
ginkgo, grape - vine and lingonberry / cranberry.
The first thing to do was to find out the widespread of products in Germanspeaking-
countries (Austria, Germany and Switzerland). Just one of the
products we found was a real pharmaceutical product (Tebofortan®); the
rest of them were nutritional supplements.
Selected products of all of the three plants were bought. We compared the
ingredients and prices of these products, package inserts and the origin
(pharmacies, chemist shops, and internet).
The fact, that the products bought in pharmacies were mostly the cheapest,
was very interesting.
We analyzed the Ginkgo-products concerning to ginkgolic acids.
Ginkgolic - acids are potential harmful substances in ginkgo biloba leaves.
The allowed maximum daily intake for humans is 5 ppm. In ginkgo -
products with higher amounts of ginkgolic acids these acids have to be
eliminated, and because of that, special ginkgo-extracts are produced.
In ginkgo-products containing high amounts of ginkgolic-acids very probably
no extracts are used, but whole ginkgo-leaves.
To detect the ginkgolic-acids, thin-layer-chromatography (qualitative
analysis) and HPLC (high performance liquid chromatography) (quantitative
analysis) were used.
In some of these products, ginkgolic-acids were notedly increased. For
Veterinary products, there are no maximum levels of ginkgolic-acids
prescribed. Some products are potentially dangerous to health for humans, because of
the notedly increased ginkgolic-acid-concentrations.