Kritische Betrachtung der zunehmenden Substitution von Phytopharmaka durch Ergänzungsmittel bei Mensch und Tier unter besonderer Berücksichtigung der Pflanzen Baldrian, Johanniskraut und Sonnenhut.
Critical view of the increasing substiution of herbal supplements by humans and animals with special references to plant Valerian, Echinacea and St. John's wort
Diplomarbeit, Vet. Med. Univ. Wien, pp. 140.
The aim of this work was a critical examination of the additives with the herbal drugs "Valeriana", "Echinacea" and "Hypericum" as active pharmaceutical ingredients. Those additives are analysed in detail in regard to their identification, priceperformance ratio, dosing and concentration and are finally compared to the pharmaceuticals with the same active ingredients. Additionally, the biologics with the agent "Valeriana" were analysed using the thin layer chromatography. For the additives which are intended either for humans or animals most of the analysed products can be evaluated as good in regard to their identification. Also the human-pharmaceuticals are mostly evaluated as good without the biologics which contain the agent "Hypericum". For the vet-pharmaceuticals on the other hand, all products can be evaluated as good. The results of the examination in regard to the price-performance ratio show big price differences also for one supplier concerning the taking of one daily dose of one herbal active ingredient. The dietary supplements are more expensive in relation to their clear concentration compared to the human-pharmaceuticals, although they are less subjected to requirements. Neverless, the costs per day for the humanpharmaceuticals are higher due to the introduction of taking and their dose of the active ingredients compared to the dietary supplements. The opposite was the case for the price-performance ratio by comparing the additives of forage and vetpharmaceuticals. The dietary supplements are completely different in regard to their daily dose compared to the human-pharmaceuticals. Therefore, they do have a much less dosing and cannot display a pharmacological effect. That means furthermore that they can be placed onto the market without any pharmaceutical control. The thin layer chromatography of the herbal drug "Baldrian" shows that the active ingredient can be observed in all investigated human-pharmaceuticals and dietary supplements but only in one of four additives of forage.