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Publication type: Diploma Thesis

Year: 2011

Author(s): Hammer, Marisa

Title: Untersuchung von Qualität und Preis von pflanzlichen Nahrungs- und Futterergänzungsmitteln im Vergleich zu Arzneimitteln im Human- und Veterinärbereich mit den Inhaltsstoffen Artischocke, Mariendistel und Weißdorn.

Other title: Analysis of quality and price of herbal food and feed supplements compared to human and veterinary drugs with the ingredients of artichoke, milk thistle and hawthorn

Source: Diplomarbeit, Vet. Med. Univ. Wien, pp. 73.


Advisor(s):

Franz Chlodwig
Hahn-Ramssl Isabella

Reviewer(s):
Dadak Agnes

Vetmed Research Units:
Institute of Animal Nutrition and Functional Plant Compounds


Graduation date: 06.12.11


Abstract:
Herbal drugs are marketed as drugs for humans and animals as well as food and feed supplements. The major barrier in obtaining the approvals and registrations of herbal medicines cause more and more pharmaceuticals companies to manufacture dietary supplements and feed additives, which are becoming increasingly important. Because dietary supplements are food, an approval is not required and the production is associated with enormous cost and time savings compared to herbal drugs. However for consumers the market of supplements is unclear and often confusing. After compiling a market overview off all products with the ingredients artichoke, milk thistle and hawthorn, some were selected and purchased. These products were checked for adequate identification, and compared with respect to price, daily dose, drug quantity and drug price. All veterinary remedies and feed supplements are complete labeled. In both products of Apomedica Braille is missing. The complete labeled medicinal products are Biogelat Leberschutzkapseln from Kwizda Pharma, Weissdorn-ratiopharm 450 mg Filmtabletten from Merckle, the products from Doppelherz aktiv (Artischocke-Mariendistel-Kombi-Kapseln, Weißdorn- Dragees and Energie-Tonikum Herz-Kreislauf) from Queisser Pharma and tetesept Mariendistel Kapseln from Merz Pharma. If you compare the prices Crataegutt drops are with 28,60 euro per gram drug by far the most expensive. In the practical part all bought artichoke products were examined for the presence of the typical plant ingredients caffeic and chlorogenic acid with the preparation of extracts and thin layer chromatography (TLC). At Apozema Mariendistel forte Dragees (Apomedica), Bio Drain (New Nordic) und Aurita Artischocke Plus (Richard Bittner) neither of the two ingredients are proven. At the other products was either caffeic or chlorogenic acid proven. At Biogelat Artischocken 3000 Dragees (Kwizda Pharma), Dr. Böhm Artischocke 450 mg Dragees (Apomedica), Heparal Dog (Navalis) and Hepar Cheval (Planta Vet) both reference substances were clearly visible in UV light.


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