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Publication type: Diploma Thesis

Year: 2011

Author(s): Hellmich, Ruth Elke

Title: Vergleich der Sicherheit und Wirksamkeit eines One-Shot-Impfstoffes mit einem Two-Shot-Impfstoff gegen Mycoplasma hyopneumoniae in einem kombinierten steirischen Schweineerzeugerbetrieb.

Other title: Comparison of the safety and efficiency of a one-shot vaccination to a two-shot vaccination against Mycoplasma hyopneumoniae in a combined Styrian swine production

Source: Diplomarbeit, Vet. Med. Univ. Wien, pp. 57.


Ritzmann Mathias

Busse Hans-Jürgen

Vetmed Research Units:
University Clinic for Swine

Graduation date: 15.12.11

This study was determined to assess the difference between a one-shot and a two-shot-vaccination against Mycoplasma hyopneumoniae, the pathogen of Enzootie Pneumonia in pigs. The assessment was effected by abattoir surveillance of the lungs of 356 pigs, of whom 185 had received the one-shot vaccine Stellamune One• (Pfizer) in the first week and 171 had received the two-shot vaccine Stellamune Mycoplasma• (Pfizer) in the first and fourth week by the livestock owner. Neither the one-shot- nor the two-shot-vaccination caused any kind of discomfort or complication to the animals. Before the start of the project, the health status of the farm was assessed by serological testing of ten randomly selected pigs and by abattoir surveillance of 141 pigs. The health status proved favourable, even though M. hyopneumoniae was detected in all diagnostic assays. Additional assessment of secondary bacterial and viral agents was performed: PRRSV was isolated in only a few cases and APP only in one case.Because of the low weight and the relatively high age of the pigs at slaughter there is reason to believe that the infection with M. hyopneumoniae takes place early in the farrowing period. The results of the abattoir surveillance did not generate any statistically significant difference between the two types of vaccination. However, a trend towards decrease in lung lesions can be detected in the one-shotvaccination. Regarding pneumonia lesions of the cranial lobe, the two-shot-vaccination tends to evolve better results. An additional comparison of seasonal groups of pigs showed no significant difference regarding the gravity of lung lesions. In conclusion it can be stated that there is no difference in a weil managed farm (from farrow-to finish production system, all-in-all-out, no introduction of foreign animals) with good health status concerning the use of a one-shot- or a two-shot-vaccination. A thorough surveillance of the pigs regarding the onset of coughing or respiratory discomfort and the compilation of a serological profile would be desirable in order to determine the time of infection.

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