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Publication type: Doctoral Thesis

Year: 2013

Author(s): Stricker, Teija Maria

Title: Eine Studie zur Überprüfung der Verträglichkeit der simultanen Anwendung eines Porcine Reproductive and Respiratory Syndrome Virus (EU-Typ) Impfstoffes und eines M. hyopneumoniae Impfstoffes unter Feldbedingungen.

Other title: A study to assess the compatibility of simultaneous use of Porcine Reproductive and Respiratory Syndrome Virus (EU-type) vaccine and Mycoplasma hyopneumoniae vaccine under field conditions

Source: Dissertation, Vet. Med. Univ. Wien, pp. 174.


Advisor(s):

Ladinig Andrea
Ritzmann Mathias

Reviewer(s):
Saalmüller Armin

Vetmed Research Units:
University Clinic for Swine


Graduation date: 22.01.13


Abstract:
M. hyopneumoniae and PRRSV vaccines are often administered in the field at the same time. The simultaneous use of the two vaccines mixed in one syringe would save labour and increase animal welfare by reducing the number of injections. The aim of this study was to compare under field conditions if the simultaneous use of both vaccinesis as compatible and effective as the separated application of both products. The randomised, controlled and blinded field trial was conducted at two pig farms in Austria. One Thousand, one week old suckling piglets were included in the study and divided into five groups. The Piglets wereeither non vaccinated or vaccinated against M. hyopneumoniae and/or PRRSV-EU-type. Blood samples were taken from the pigs and analysed serologically by ELISA for the presence of PRRSV and M. hyopneumoniae antibodies. At the slaughterhouse, a lung scoring for M. hyopneumoniae induced lung lesions was performed. Clinical examinations were carried out and mortality, morbidity, local reactions and body weight were measured. When comparing the results of the clinical parameters, mortality and ADWG between the different groups, no significant differences were verified, as no clinically relevant systemic or local reactions were detectable following vaccination. Comparing the severity code of the lesions of affected lungs, the lung score from the simultaneously vaccinated pigswas significantly lower than the score from the non-vaccinated pigs. Regarding the serological results, significant differences were detected forM. hyopneumoniae antibodies. The percentage of M. hyopneumoniaeantibody positive pigs was significantly higher in the vaccinated groups than in the non-vaccinated groups. We can conclude that the simultaneous application of both vaccines is as compatible as the single application of the two vaccines.

Keywords:
PRRSV / Mycoplasma hyopneumoniae / simultaneous vaccination / field study


Publication(s) resulting from University thesis:

Stricker, TM; Weissenbacher-Lang, C; Ritzmann, M; Ladinig, A (2013): A study to assess the compatibility of simultaneous use of porcine reproductive and respiratory syndrome virus (EU-type) vaccine and Mycoplasma hyopneumoniae vaccine under field conditions. Berl Munch Tierarztl Wochenschr. 2013; 126(5-6):189-196

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