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Publication type: Diploma Thesis

Year: 2013

Author(s): Kreinöcker, Karin

Title: Atrophie der Milz bei Zuchtsauen - Zwei Fallberichte.

Other title: Athropic spleen of sows - Two case reports

Source: Diplomarbeit, Vet. Med. Univ. Wien, pp. 31.


Advisor(s):

Hennig-Pauka Isabel

Reviewer(s):
Weissenböck Herbert

Vetmed Research Units:
University Clinic for Swine


Graduation date: 23.05.13


Abstract:
The spleen is necessary to eliminate altered erythrocytes and pathogens from the blood, to activate lymphocytes, for the presentation of blood-borne antigens by macrophages and, if necessary for extramedullary haemopoesis. (MCORIST u. SIMS, 1996; MEBIUS u. KRAAL, 2005). Individuals without a spleen are more vulnerable to bacterial sepsis, which can result in a fulminant progress (DAVIDSON u. WALL, 2001). The so called overwhelming post-splenectomy infection (OPSI) is characterized by meningitis, pneumonia and fulminating sepsis. After a short prodromal phase with fever, shivering, myalgia, diarrhoea and vomiting, septic shock follows within a few hours. Hypotension and disseminated intravascular coagulation followed by multiorgan failure and death are the consequence (SABATINO et al., 2011). Similar disease symptoms occurred on two farm s. From each farm one sow which had been died suddenly was necropsied. During necropsy atrophic spleens were found in both sows. The hypothesis from this case report was that an atrophic spleen reduces the resistance against ubiquitous pathogens.


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