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Publication type: Journal Article
Document type: Full Paper

Year: 2005

Author(s): Zola, H; Swart, B; Nicholson, I; Aasted, B; Bensussan, A; Boumsell, L; Buckley, C; Clark, G; Drbal, K; Engel, P; Hart, D; Horejsí, V; Isacke, C; Macardle, P; Malavasi, F; Mason, D; Olive, D; Saalmueller, A; Schlossman, SF; Schwartz-Albiez, R; Simmons, P; Tedder, TF; Uguccioni, M; Warren, H

Title: CD molecules 2005: human cell differentiation molecules.

Source: Blood. 2005; 106(9):3123-3126

Authors Vetmeduni Vienna:

Saalmüller Armin

Vetmed Research Units
Institute of Immunology

The immune system works through leukocytes interacting with each other, with other cells, with tissue matrices, with infectious agents, and with other antigens. These interactions are mediated by cell-surface glycoproteins and glycolipids. Antibodies against these leukocyte molecules have provided powerful tools for analysis of their structure, function, and distribution. Antibodies have been used widely in hematology, immunology, and pathology, and in research, diagnosis, and therapy. The associated CD nomenclature is commonly used when referring to leukocyte surface molecules and antibodies against them. It provides an essential classification for diagnostic and therapeutic purposes. The most recent (8th) Workshop and Conference on Human Leukocyte Differentiation Antigens (HLDA), held in Adelaide, Australia, in December 2004, allocated 95 new CD designations and made radical changes to its aims and future operational strategy in order to maintain its relevance to modern human biology and clinical practice.

Keywords Pubmed: Antigens, CD/classification*
Antigens, CD/immunology
Cell Differentiation
Reproducibility of Results
Terminology as Topic*

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