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Type of publication: Journal Article
Type of document: Full Paper

Year: 2001

Authors: Nechtelberger, D; Pires, V; Söolknet, J; Stur, ; Brem, G; Mueller, M; Mueller, S

Title: Intramuscular fat content and genetic variants at fatty acid-binding protein loci in Austrian pigs.

Source: J Anim Sci (79), 11 2798-2804.

Authors Vetmeduni Vienna:

Brem Gottfried
Müller Mathias
Müller Simone
Sommerfeld-Stur Irene

Vetmed Research Units
Institute of Animal Breeding and Genetics

Intramuscular fat is an important meat quality trait in pig production. Previously, genetic variants of the heart fatty acid-binding protein (H-FABP) gene and the adipocyte fatty acid-binding protein (A-FABP) gene were suggested to be associated with intramuscular fat content. The objective of this investigation was to study these associations in the three most important Austrian breeding populations (Piétrain, Large White, and Landrace). Restriction fragment length polymorphism analysis of the H-FABP gene revealed a new MspI polymorphic site and genetic variation in all three breeds. Microsatellite analysis of the A-FABP locus showed up to nine different microsatellite alleles segregating. In Austrian breeds, no significant influence of the A-FABP and H-FABP gene polymorphisms on intramuscular fat could be detected. We also evaluated possible associations between the genetic variations at the H-FABP and A-FABP loci and other growth and carcass traits (average daily gain, feed conversion ratio, lean meat content, pH values, meat color, and drip loss). With regard to the extent of the effects, these genetic markers cannot be recommended for selection on growth and carcass traits in Austrian breeding populations.

Keywords Pubmed: Adipocytes/metabolism
Adipose Tissue/anatomy & histology*
Adipose Tissue/metabolism
Carrier Proteins/genetics*
Carrier Proteins/metabolism
Carrier Proteins/physiology
Fatty Acid-Binding Proteins
Gene Expression Regulation
Gene Frequency
Genetic Markers
Genetic Variation
Muscle, Skeletal/anatomy & histology*
Muscle, Skeletal/metabolism
Neoplasm Proteins*
Polymerase Chain Reaction/veterinary
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Swine/anatomy & histology

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