Roell, W; Lu, ZJ; Bloch, W; Siedner, S; Tiemann, K; Xia, Y; Stoecker, E; Fleischmann, M; Bohlen, H; Stehle, R; Kolossov, E; Brem, G; Addicks, K; Pfitzer, G; Welz, A; Hescheler, J; Fleischmann, BK
Cellular cardiomyoplasty improves survival after myocardial injury.
Circulation. 2002; 105(20):2435-2441
Authors Vetmeduni Vienna:
Cellular cardiomyoplasty is discussed as an alternative therapeutic approach to heart failure. To date, however, the functional characteristics of the transplanted cells, their contribution to heart function, and most importantly, the potential therapeutic benefit of this treatment remain unclear.
Animals Blotting, Western Cardiomyoplasty/methods* Cell Differentiation Cell Survival Cell Transplantation/methods* Disease Models, Animal Echocardiography Electrophysiology Fetal Tissue Transplantation Genes, Reporter Graft Survival Heart Function Tests Male Mice Mice, Inbred C57BL Mice, Transgenic Myocardial Contraction Myocardial Infarction/pathology Myocardial Infarction/therapy* Myocardial Infarction/ultrasonography Myocardium/pathology* Survival Rate Treatment Outcome Ventricular Dysfunction, Left/therapy Ventricular Dysfunction, Left/ultrasonography