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Selected Publication:

Publication type: Journal Article
Document type: Full Paper

Year: 2000

Author(s): Mayr, B; Brem, G; Reifinger, M

Title: Absence of S100A4 (mts1) gene mutations in various canine and feline tumours. Detection of a polymorphism in feline S100A4 (mts1).

Source: J Vet Med A Physiol Pathol Clin Med. 2000; 47(2):123-128

Authors Vetmeduni Vienna:

Brem Gottfried
Reifinger Martin

Vetmed Research Units
Institute of Animal Breeding and Genetics
Institute of Pathology

Ninety canine and 101 feline tumours of various types were investigated for gene mutations in the coding regions of the metastasis-associated gene S100A4 (mts1). No gene mutations were present in the analysed genomic area. A widespread histidine/tyrosine polymorphism was detected in codon 17 of S100A4.

Keywords Pubmed: Amino Acid Sequence
Base Sequence
Cat Diseases/genetics*
Cyclin-Dependent Kinase Inhibitor p16/chemistry
Cyclin-Dependent Kinase Inhibitor p16/genetics*
DNA, Neoplasm/chemistry
DNA, Neoplasm/isolation & purification
Dog Diseases/genetics*
Electrophoresis, Agar Gel/veterinary
Molecular Sequence Data
Polymerase Chain Reaction/veterinary
Polymorphism, Genetic/genetics
Sequence Alignment
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid

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