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Selected Publication:

Publication type: Journal Article
Document type: Full Paper

Year: 2000

Author(s): Mayr, B; Brem, G; Reifinger, M

Title: Absence of S100A4 (mts1) gene mutations in various canine and feline tumours. Detection of a polymorphism in feline S100A4 (mts1).

Source: J Vet Med A Physiol Pathol Clin Med. 2000; 47(2):123-128



Authors Vetmeduni Vienna:

Brem Gottfried
Reifinger Martin

Vetmed Research Units
Institute of Animal Breeding and Genetics
Institute of Pathology


Abstract:
Ninety canine and 101 feline tumours of various types were investigated for gene mutations in the coding regions of the metastasis-associated gene S100A4 (mts1). No gene mutations were present in the analysed genomic area. A widespread histidine/tyrosine polymorphism was detected in codon 17 of S100A4.

Keywords Pubmed: Amino Acid Sequence
Animals
Base Sequence
Cat Diseases/genetics*
Cats
Cyclin-Dependent Kinase Inhibitor p16/chemistry
Cyclin-Dependent Kinase Inhibitor p16/genetics*
DNA, Neoplasm/chemistry
DNA, Neoplasm/isolation & purification
Dog Diseases/genetics*
Dogs
Electrophoresis, Agar Gel/veterinary
Molecular Sequence Data
Neoplasms/genetics
Neoplasms/veterinary*
Polymerase Chain Reaction/veterinary
Polymorphism, Genetic/genetics
Sequence Alignment
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid


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