University of Veterinary Medicine Vienna - Research portal

Diagrammed Link to Homepage University of Veterinary Medicine, Vienna

Selected Publication:

Publication type: Journal Article
Document type: Full Paper

Year: 2000

Author(s): Steinborn, R; Schinogl, P; Zakhartchenko, V; Achmann, R; Schernthaner, W; Stojkovic, M; Wolf, E; Müller, M; Brem, G

Title: Mitochondrial DNA heteroplasmy in cloned cattle produced by fetal and adult cell cloning.

Source: Nat Genet. 2000; 25(3):255-257



Authors Vetmeduni Vienna:

Brem Gottfried
Müller Mathias
Steinborn Ralf

Vetmed Research Units
Institute of Animal Breeding and Genetics


Abstract:
Mammals have been cloned from adult donor cells. Here we report the first cases of mitochondrial DNA (mtDNA) heteroplasmy in adult mammalian clones generated from fetal and adult donor cells. The heteroplasmic clones included a healthy cattle equivalent of the sheep Dolly, for which a lack of heteroplasmy was reported.

Keywords Pubmed: Animals
Cattle
Cells, Cultured
Cloning, Organism*
DNA, Mitochondrial*
Epithelial Cells/cytology
Fibroblasts/cytology
Genetic Variation*


© University of Veterinary Medicine ViennaHelp and Downloads