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Selected Publication:

Publication type: Journal Article
Document type: Full Paper

Year: 2000

Author(s): Mayr, B; Wilhelm, B; Reifinger, M; Brem, G

Title: Absence of p21 WAF1 and p27 kip1 gene mutations in various feline tumours.

Source: Vet Res Commun. 2000; 24(2):115-124



Authors Vetmeduni Vienna:

Brem Gottfried
Reifinger Martin

Vetmed Research Units
Institute of Animal Breeding and Genetics
Institute of Pathology


Abstract:
The coding regions of tumour suppressor and cell cycle regulatory genes p21 WAF1 and p27 Kip1 were investigated in 101 feline tumours of various types. No damaging mutations were present in the analysed areas of the genes.

Keywords Pubmed: Adenocarcinoma/genetics
Adenocarcinoma/veterinary
Amino Acid Sequence
Animals
Base Sequence
Carcinoma, Basal Cell/genetics
Carcinoma, Basal Cell/veterinary
Carcinoma, Squamous Cell/genetics
Carcinoma, Squamous Cell/veterinary
Cat Diseases/genetics*
Cats
Cell Cycle Proteins*
Cyclin-Dependent Kinase Inhibitor p21
Cyclin-Dependent Kinase Inhibitor p27
Cyclins/genetics*
DNA Primers/chemistry
DNA, Neoplasm/chemistry
DNA, Neoplasm/genetics
DNA, Neoplasm/isolation & purification
Female
Fibrosarcoma/genetics
Fibrosarcoma/veterinary
Histiocytoma, Benign Fibrous/genetics
Histiocytoma, Benign Fibrous/veterinary
Mammary Neoplasms, Animal/genetics
Melanoma/genetics
Melanoma/veterinary
Microtubule-Associated Proteins/genetics*
Molecular Sequence Data
Mutation
Neoplasms/genetics
Neoplasms/veterinary*
Pancreatic Neoplasms/genetics
Pancreatic Neoplasms/veterinary
Polymerase Chain Reaction/veterinary
Sequence Analysis, DNA
Tumor Suppressor Proteins*


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